Results 21 to 30 of about 2,021,769 (367)

Sepsis—A Retrospective Cohort Study of Bloodstream Infections [PDF]

Antibiotics, 2020
Bloodstream infections (BSIs) are among the leading causes of morbidity and mortality worldwide, among infectious diseases. Local knowledge of the main bacteria involved in BSIs and their associated antibiotic susceptibility patterns is essential to rationalize the empiric antimicrobial therapy.
Santella B., Folliero V., Pirofalo G. M., Serretiello E., Zannella C., Moccia G., Santoro E., Sanna G., Motta O., Caro F. D., Pagliano P., Capunzo M., Galdiero M., Boccia G., Franci G.   +14 more
openaire   +4 more sources

Paroxetine and Mortality in Heart Failure: A Retrospective Cohort Study

Frontiers in Cardiovascular Medicine, 2022
IntroductionParoxetine is a GRK2 inhibitor that has been widely used to treat depression and anxiety over the last few decades. The inhibition of GRK2 has been studied extensively in vivo; however, evidence of its impact on heart failure remains scarce ...
Hongxuan Xu, Hongxuan Xu, Lingbing Meng, Lingbing Meng, Huanyu Long, Yueping Shi, Yunqing Liu, Yunqing Liu, Li Wang, Li Wang, Deping Liu, Deping Liu, Deping Liu   +12 more
doaj   +1 more source

Early Discontinuation of Apremilast in Patients with Psoriasis and Gastrointestinal Comorbidities: Rates and Associated Risk Factors

Dermatology and Therapy, 2023
Introduction Apremilast, the first oral targeted treatment for moderate to severe psoriasis, is associated with diarrhea, nausea, and vomiting, which have contributed to treatment discontinuation.
Lana Schmidt, Ching An Wang, Vardhaman Patel, David Davidson, Samaneh Kalirai, Ankita Panda, Lauren Seigel   +6 more
doaj   +1 more source

Cohort Studies: Prospective versus Retrospective [PDF]

Nephron Clinical Practice, 2009
Cohort studies form a suitable study design to assess associations between multiple exposures on the one hand and multiple outcomes on the other hand. They are especially appropriate to study rare exposures or exposures for which randomization is not possible for practical or ethical reasons.
Carmine Zoccali, Kitty J Jager, Friedo W. Dekker, Anne M. Euser   +3 more
openaire   +3 more sources

Infective endocarditis: a retrospective cohort study [PDF]

QJM: An International Journal of Medicine, 2019
Abstract Background Infective endocarditis (IE) is a potentially life-threatening infection of the heart’s endocardial surface. Despite advances in the diagnosis and management of IE, morbidity and mortality remain high.
S O'Rourke, Caroline Daly, Peter Crean, A Buckley, V Young, Andrew O. Maree, M Tolan, R Ryan, Ross T. Murphy, C O’Connor, B. Foley, B O'Connell   +11 more
openaire   +2 more sources

Tuberculosis in the ICU: a retrospective cohort study [PDF]

Critical Care, 2015
To describe the characteristics of the patients with tuberculosis (TB) requiring intensive care and to identify the factors associated with in-hospital mortality in an ICU in Portugal.
Lurdes Santos, António Sarmento, Paulo Figueiredo, Alcina Ferreira, Cláudia Alves, S. Xerinda, Raquel Duro   +6 more
openaire   +2 more sources

Real-world effectiveness of steroids in severe COVID-19: a retrospective cohort study

BMC Infectious Diseases, 2022
Introduction Randomised controlled trials have shown that steroids reduce the risk of dying in patients with severe Coronavirus disease 2019 (COVID-19), whilst many real-world studies have failed to replicate this result. We aim to investigate real-world
Wenjuan Wang, Luke B Snell, Davide Ferrari, Anna L Goodman, Nicholas M Price, Charles D Wolfe, Vasa Curcin, Jonathan D Edgeworth, Yanzhong Wang   +8 more
doaj   +1 more source

There is no age limit for methadone: a retrospective cohort study [PDF]

Substance Abuse Treatment, Prevention, and Policy, 2011
Data from the US indicates that methadone-maintained populations are aging, with an increase of patients aged 50 or older. Data from European methadone populations is sparse. This retrospective cohort study sought to evaluate the age trends and related developments in the methadone population of Basel-City, Switzerland.The study included methadone ...
Dürsteler-MacFarland, Kenneth M., Vogel, Marc, Wiesbeck, Gerhard A., Petitjean, Sylvie A.   +3 more
openaire   +4 more sources

Brucellosis in Qatar: A retrospective cohort study

Qatar Medical Journal, 2014
Background:We conducted a retrospective cohort study to evaluate the clinical manifestations, laboratory findings, complications and treatment of brucellosis in the State of Qatar.Methods:The medical records of patients in Hamad Medical Corporation, Doha, Qatar were reviewed from January 2000 to December 2006.
Walid Ibrahim, Mohamed Yahya Mohamed, Ali Rahil, Muftah Othman   +3 more
openaire   +3 more sources

Development and validation of an interpretable machine learning-based calculator for predicting 5-year weight trajectories after bariatric surgery: a multinational retrospective cohort SOPHIA study [PDF]

, 2023
Background Weight loss trajectories after bariatric surgery vary widely between individuals, and predicting weight loss before the operation remains challenging. We aimed to develop a model using machine learning to provide individual preoperative prediction of 5-year weight loss trajectories after surgery.
arxiv   +1 more source