Results 221 to 230 of about 43,695,403 (371)

Tendencias y pronósticos de las infecciones nosocomiales en la provincia de Cienfuegos

open access: yesRevista Cubana de Higiene y Epidemiología
Se realizó un estudio descriptivo retrospectivo sobre el comportamiento de las infecciones nosocomiales en la provincia de Cienfuegos durante el período de 1989-1998 para analizar las tendencias y elaborar pronósticos para los años 1999, 2000 y 2001.
Marta Luján Hernández
doaj  

The Prevalence of Malaria in Tselemti Wereda, North Ethiopia: A Retrospective Study

open access: diamond, 1970
Meresa Shiferaw   +5 more
openalex   +2 more sources

Piezo1 Activation Improves NSCLC Liver Metastasis Immunotherapy by Overriding Matrix Stiffness‐Mediated Bimodal PD‐L1/CXCL10 Regulation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Piezo1 activation enhances FAK‐YAP‐mediated upregulation of PD‐L1 and CXCL10, thereby promoting an immunotherapy‐responsive tumor microenvironment in NSCLC. Cyclic stretch modulates the PD‐L1/CXCL10 response to ECM stiffness, reshaping their expression dynamics.
Tian Zhang   +11 more
wiley   +1 more source

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

open access: yesAdvanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu   +18 more
wiley   +1 more source

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