Results 51 to 60 of about 2,068,929 (319)

Digital citizen science for ethical surveillance of physical activity among youth: mobile ecological momentary assessments vs. retrospective recall [PDF]

arXiv, 2023
Physical inactivity is the fourth leading risk factor of mortality globally. Hence, understanding the physical activity (PA) patterns of youth is essential to manage and mitigate non-communicable diseases. As digital citizen science approaches utilizing citizen-owned smartphones to ethically obtain PA big data can transform PA surveillance, this study ...
arxiv  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Retrospective-prospective symmetry in the likelihood and Bayesian analysis of case-control studies [PDF]

Biometrika (2014) 101 (1), pages 189-204, 2012
Prentice & Pyke (1979) established that the maximum likelihood estimate of an odds-ratio in a case-control study is the same as would be found by running a logistic regression: in other words, for this specific target the incorrect prospective model is inferentially equivalent to the correct retrospective model.
arxiv   +1 more source

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

A critical analysis of the decreasing trends in tuberculosis cure indicators in Brazil, 2001-2022 [PDF]

Jornal Brasileiro de Pneumologia
Objective: To analyze the temporal trend of tuberculosis cure indicators in Brazil. Methods: An ecological time-series study using administrative data of reported cases of the disease nationwide between 2001 and 2022.
Gabriel Pavinati, Lucas Vinícius de Lima, Pedro Henrique Paiva Bernardo, Jhenicy Rubira Dias, Bárbara Reis-Santos, Gabriela Tavares Magnabosco   +5 more
doaj   +1 more source

Some Aspects of Retrospective Studies

Revista Brasileira de Cancerologia, 2023
The statement that a disease and a characteristic are associated can be Tinterpreted in a number of different ways. (1) The deliberate introduction of the characteristic into a subgroup of a population will be followed by an altered incidence of the ...
William Haenszel
doaj   +1 more source

Retrospective, Observational Studies for Estimating Vaccine Effects on the Secondary Attack Rate of SARS-CoV-2 [PDF]

arXiv, 2022
COVID-19 vaccines are highly efficacious at preventing symptomatic infection, severe disease, and death. Most of the evidence that COVID-19 vaccines also reduce transmission of SARS-CoV-2 is based on retrospective, observational studies. Specifically, an increasing number of studies are evaluating vaccine efficacy against the secondary attack rate of ...
arxiv  

Deconfounded Image Captioning: A Causal Retrospect [PDF]

, 2020
Dataset bias in vision-language tasks is becoming one of the main problems which hinders the progress of our community. Existing solutions lack a principled analysis about why modern image captioners easily collapse into dataset bias. In this paper, we present a novel perspective: Deconfounded Image Captioning (DIC), to find out the answer of this ...
arxiv   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source