Results 71 to 80 of about 2,449,778 (334)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Elevated Risk of Stroke in Young Adults After Traumatic Brain Injury: A Nationwide Study of 1 Million Individuals

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Although stroke is commonly perceived as occurring in older adults, traumatic brain injury, one of the risk factors for stroke, is a leading cause of death in the younger adults.
Yoonjeong Choi, Jooeun Jeon, Eun Jin Ha, Chi Kyung Kim, Han Gil Seo, Byung‐Mo Oh, Ja‐Ho Leigh   +6 more
doaj   +1 more source

Maxillofacial infection. A retrospective evaluation of eight years

Brazilian Journal of Oral Sciences, 2015
Aim: To evaluate medical records from patients who had maxillofacial infections between August 2002 and May 2010. Methods: Analysis of 157 patients’ data looking for epidemiology, causes of the infection, type of treatment established and complications ...
Bruno Veronez, Fernando Pando de Matos, Marcelo Silva Monnazzi, Alexander Tadeu Sverzut, Cássio Edvard Sverzut, Alexandre Elias Trivellato   +5 more
doaj   +1 more source

Pediatric Rotavirus Gastroenteritis: A 2 year Analysis to Understand Current Prevalence in Mumbai [PDF]

, 2011
Many studies have established the high prevalence of paediatric Rotavirus gastroenteritis in India. The importance of rapid diagnosis of rotavirus infection has also been stressed upon, to initiate prompt rehydration therapy and prevent unnecessary use ...
Bhatia, S, Dhole, V, Kothari, N, Nerurkar, V   +3 more
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Predictability and Effectiveness of Nuvola® Aligners in Dentoalveolar Transverse Changes: A Retrospective Study [PDF]

, 2023
Angelo Michele Inchingolo, Sabino Ceci, Giovanni Coloccia, Daniela Azzollini, Giuseppina Malcangi, Antonio Mancini, Francesco Inchingolo, Paolo Trerotoli, Gianna Dipalma, Assunta Patano   +9 more
openalex   +1 more source

Soft systems methodology: a context within a 50-year retrospective of OR/MS [PDF]

, 2005
Soft systems methodology (SSM) has been used in the practice of operations research and management science OR/MS) since the early 1970s. In the 1990s, it emerged as a viable academic discipline.
Abbott A., Ackoff R. L., Ackoff R. L., Arnold Reisman, Assad A. A., Beer S., Berkeley G., Blackett P. M. S., Blair L. H., Brocklesby J., Checkland P., Checkland P., Churchman C. W., Churchman C. W., Churchman C. W., Churchman C. W., Coyle R. G., Eden C., Finlay P. N., Forrester J. W., Forrester J. W., Forrester J. W., Forrester J. W., Fortuin L., Gass S. I., Glans T. B., Hermann C. C., Jackson M. C., Jackson M. C., Jackson M. C., Jackson M. C., Johnston R. A., Kahn H., Kahn H., Kelly G. A., Levin R. I., Lilien G. L., Majone G., Malouin J. L., Mason R. O., McCloskey J. F., Meadows D. L., Meadows D. L., Mingers J., Mingers J., Mingers J., Mintzberg H., Miser H. J., Miser H. J., Miser H. J., Mitchell G., Muhittin Oral, Muller-Merbach H., Naylor T. H., Nissen D., Palding E., Pidd M., Pounds W. F., Quade E. S., Randers J., Ranyard J., Ravetz L. R., Reisman A., Reisman A., Reisman A., Reisman A., Reisman A., Roche J. G., Rosenhead J. V., Roy H. J. H., Schon D. A., Stainton R. S., Tidman K. R., Toulmin S., Woolley R. N., Yewlett C. J. L.   +75 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Retrospective study of facial fractures

Annals of Maxillofacial Surgery, 2018
The aim of this study was to give an insight into the retrospective analysis of a number of maxillofacial trauma cases reported to our institute and research center.The data for this study was obtained from the medical records and outpatient prescription slips of cases treated at the Oral and Maxillofacial Surgery Department from 2010 to 2016. Etiology,
Kaura, Sameer, Kaur, Paramjot, Bahl, Rashi, Bansal, Sumit, Sangha, Prineet   +4 more
openaire   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source