Results 41 to 50 of about 3,101,407 (362)

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Canine lymphoma: a retrospective study (2009-2010) [PDF]

, 2012
This study reviews the medical records of 56 dogs diagnosed with lymphoma based on the cytological and/or histological results between January 1, 2009 and December 31, 2010.
Daminet, Sylvie, Mortier, Femke, Van de Maele, Isabel, Vandenabeele, Sophie   +3 more
core   +1 more source

A Retrospective Observational Single-Centre Study on the Burden of Immune Thrombocytopenia (ITP) [PDF]

, 2012
Background: German data on economic consequences of immune thrombocytopenia (ITP) are limited. Patients and Methods: A retrospective, observational study based on chart review of adult patients with a confirmed diagnosis of ITP was conducted at a German ...
Ackermann, Birgit, Bauer, Matthäus, Baumann, Anja, Berger, Karin, Ostermann, Helmut, Schopohl, Dorothee, Shlaen, Rita   +6 more
core   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Paroxetine and Mortality in Heart Failure: A Retrospective Cohort Study

Frontiers in Cardiovascular Medicine, 2022
IntroductionParoxetine is a GRK2 inhibitor that has been widely used to treat depression and anxiety over the last few decades. The inhibition of GRK2 has been studied extensively in vivo; however, evidence of its impact on heart failure remains scarce ...
Hongxuan Xu, Hongxuan Xu, Lingbing Meng, Lingbing Meng, Huanyu Long, Yueping Shi, Yunqing Liu, Yunqing Liu, Li Wang, Li Wang, Deping Liu, Deping Liu, Deping Liu   +12 more
doaj   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Surgical management of thyroid tumor: single institutional experience of Eastern province of Saudi Arabia [PDF]

Korean Journal of Clinical Oncology, 2014
Purpose: To review the pattern of thyroid tumor, demographic data of the patients, sensitivity, and specificity of fine needle aspiration cytology. Methods: This is a retrospective analysis of patients who underwent total or near-total thyroidectomy at ...
Ali M. Al-Amri
doaj   +1 more source

A Retrospective Study of the Efficacy of Albendazole and Diethylcarbamazine for the Treatment of Human Toxocariasis

Pathogens, 2022
In the Department of Parasitology and Mycology of Toulouse University Hospitals, patients presenting with common/covert toxocariasis were treated either with albendazole (39 cases) or with diethylcarbamazine (32 cases).
Jean-François Magnaval, Judith Fillaux, Antoine Berry   +2 more
doaj   +1 more source

Borderline Ovarian Malignancies : A Single Institute Retrospective Study. [PDF]

, 2013
Background: Borderline ovarian tumors are histologically characterized as epithelial tumors with a stratified growth pattern but without destructive stromal invasion.
Bafna, UD, Bhise, R, Guruprasad, B, Kundargi, R, Pallavi, R, Rathod, R, Shakuntala, PN, Shobha, K, Umadevi, K   +8 more
core  

Prospective memory functioning among ecstasy/polydrug users: evidence from the Cambridge Prospective Memory Test (CAMPROMPT) [PDF]

, 2011
Rationale: Prospective memory (PM) deficits in recreational drug users have been documented in recent years. However, the assessment of PM has largely been restricted to self-reported measures that fail to capture the distinction between event-based and
A Costa, A Miyake, A Rey, BA Wilson, BA Wilson, BG Tabachnick, C Montgomery, C Montgomery, C Montgomery, C Thompson, Catharine Montgomery, CC Adda, D Tomasi, DM Spooner, F Hadjiefthyvoulou, Florentia Hadjiefthyvoulou, HC Fox, HG Pope Jr, J Fleming, J Okuda, J Raven, J Rodgers, J Rodgers, JD Henry, JE Fisk, JE Fisk, John E. Fisk, JR Crawford, JR Leitz, KL Medina, L Reneman, L Reneman, M Kliegel, MA McDaniel, N Solowij, Nikola Bridges, PG Rendell, PG Rendell, PG Rendell, PN Murphy, PW Burgess, R Hannon, RA Dixon, RL Marsh, RM Roth, S McHale, SJ Gilbert, T Martin, T Paraskevaides, TM Heffernan, TM Heffernan, Y Goto, YCT Groot   +52 more
core   +1 more source