Results 51 to 60 of about 3,101,407 (362)

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

A Retrospective Study of Verruca

Berkala Ilmu Kesehatan Kulit dan Kelamin, 2022
Background: Verruca (non genital warts) is a quite common public health problem caused by viral infection of low risk Human Papilloma Virus (HPV) types, risking patients of all backgrounds. There is still no ideal treatment for verruca with little knowledge regarding the effectiveness of the available therapies, which results in the lack of therapeutic
Arisia Fadila, Iskandar Zulkarnain, M. Yulianto Listiawan, Afif Nurul Hidayati, Sawitri Sawitri, Diah Indramaya, null Budi Utomo   +6 more
openaire   +2 more sources

Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study [PDF]

, 2019
BACKGROUND: For virtually every patient with colorectal cancer (CRC), hematoxylin-eosin (HE)-stained tissue slides are available. These images contain quantitative information, which is not routinely used to objectively extract prognostic biomarkers.
Brenner, H., Chang-Claude, J., Charoentong, P., Ferber, D., Gaiser, T., Halama, N., Herpel, E., Hoffmeister, M., Jansen, L., Jäger, D., Kather, J. N., Krisam, J., Luedde, T., Marx, A., Reyes-Aldasoro, C. C., Valous, N. A., Weis, C. A., Zörnig, I.   +17 more
core   +2 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Neurogenic tumors of parapharyngeal space – Clinical evaluation and management: Our experience

Journal of Head & Neck Physicians and Surgeons, 2021
Context: Neurogenic tumors are the second most common parapharyngeal space (PPS) lesions, with schwannoma being the most common neurogenic tumor seen. PPS tumors account for 0.5% of all head-and-neck masses, and most surgeons might not encounter it in ...
M B Bharathi, B S Rakesh, Babu Amabale Rudrappa, Nitish Aggarwal, Kumar Shankar de   +4 more
doaj   +1 more source

Complications of exodontia: A retrospective study

Indian Journal of Dental Research, 2011
The purpose of this study was to analyze the incidence of various complications following routine exodontia performed using fixed protocols.A total of 22,330 extractions carried out in 14,975 patients, aged between 14 and 82 years, who reported to the Department of Oral and Maxillofacial Surgery at Padmashree Dr. D. Y. Patil Dental College and Hospital,
Shruti Tejprakash Kakkar, Gokul Venkateshwar, Mukul Padhye, Aman Rajiv Khosla   +3 more
openaire   +4 more sources

Retrospective study of more than 9000 feline cutaneous tumours in the UK: 2006–2013 [PDF]

, 2017
The aim of the study was to utilise a large database available from a UK-based, commercial veterinary diagnostic laboratory to ascertain the prevalence of different forms of cutaneous neoplasia within the feline population, and to detect any breed, sex ...
Dobromylskyj, M J, Ho, N T, Smith, K C
core   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

Early Discontinuation of Apremilast in Patients with Psoriasis and Gastrointestinal Comorbidities: Rates and Associated Risk Factors

Dermatology and Therapy, 2023
Introduction Apremilast, the first oral targeted treatment for moderate to severe psoriasis, is associated with diarrhea, nausea, and vomiting, which have contributed to treatment discontinuation.
Lana Schmidt, Ching An Wang, Vardhaman Patel, David Davidson, Samaneh Kalirai, Ankita Panda, Lauren Seigel   +6 more
doaj   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source