Results 51 to 60 of about 6,011,051 (287)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The Impact of Investment Horizon on the Return and Risk of Investments in Securities in Lithuania

open access: yesOrganizations and Markets in Emerging Economies, 2016
The paper focuses on the impact of time horizon on risk and return, which usually is the object of discussions about “stock versus bond”. The aim of this paper is to investigate the transformation of risk and return when increasing the investment term ...
Laimutė Urbšienė   +2 more
doaj   +1 more source

Viability of Risk-return Trade-off within a South African Context

open access: yesJournal of Accounting and Investment, 2022
Research aims: This study aimed to determine whether systematic risk and return are related to each other. It answered the research question: Is it realistic for investors to expect high returns when their investments are associated with more riskiness ...
Natasha Robbetze   +1 more
doaj   +1 more source

The Return of the Rogue [PDF]

open access: yes, 2009
The “rogue trader”—a famed figure of the 1990s—recently has returned to prominence due largely to two phenomena. First, recent U.S. mortgage market volatility spilled over into stock, commodity, and derivative markets worldwide, causing large financial ...
Krawiec, Kimberly D.
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Return to the Poissonian City

open access: yes, 2014
Consider the following random spatial network: in a large disk, construct a network using a stationary and isotropic Poisson line process of unit intensity.
Kendall, Wilfrid S.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Distribution of Returns on Currency Exchange Rates and Bitcoin Transaction Values in G7 Countries

open access: yesRomanian Economic Journal
In this study, we evaluated the distribution of return on exchange rates of the currencies of G7 countries and also estimated the dynamic effect of Bitcoin transaction prices on currency return in the selected G7 countries.
David Umoru, Beauty Igbinovia
doaj   +1 more source

Implementation of risk in the evaluation of investment projects [PDF]

open access: yesВојно дело, 2015
Making the investment decisions means making some of the most subtle and most important decisions with long-term implications. Investors expect their investments to bring them returns greater than the invested funds, i.e.
Brzaković Tomislav D.   +2 more
doaj   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

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