Results 51 to 60 of about 2,673,482 (287)

Information Sharing and Decision-Making: Attempts by Ghanaian Return Migrants to Enter through Libya

open access: yesSocial Inclusion, 2021
This article examines the relationship between irregular migration, access to information and migration decisions. Using semi-structured interviews of thirty irregular return migrants who failed to reach their European destinations through Libya, I show ...
Elizabeth Koomson-Yalley
doaj   +1 more source

Return Migration and Occupational Choice [PDF]

open access: yesSSRN Electronic Journal, 2009
This paper explores the impact of return migration on the Albanian economy by analysing the occupational choice of return migrants while explicitly differentiating between self-employment as either own account work or entrepreneurship. After taking into account the possible sample selection into return migration, we find that the own account workers ...
Piracha, Matloob, Vadean, Florin
openaire   +4 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Do Return Migration Policies Matter? A typology of young Romanian returnees’ attitudes towards return policies

open access: yesSocial Change Review, 2018
During the last decades, the interest in migration policies has increased, both at institutional level and in academia. However, if the scientific understanding of policies associated with migration at destination has tremendously advanced, our knowledge
Șerban Monica, Croitoru Alin
doaj   +1 more source

Return Policies and Everyday Resistance: An Exploration of Nigerian Migrants’ Experiences in Austria

open access: yessozialpolitik.ch, 2023
This article delves into the nuances of resistance among Nigerian migrants in Austria, situated within the larger framework of European migration. Against the backdrop of the stringent migration regulations implemented in Austria during the 2015 long ...
Simona Schreier
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Return Migration as Failure or Success?: The Determinants of Return Migration Intentions Among Moroccan Migrants in Europe. [PDF]

open access: yesJ Int Migr Integr, 2015
Different migration theories generate competing hypotheses with regard to determinants of return migration. While neoclassical migration theory associates migration to the failure to integrate at the destination, the new economics of labour migration sees return migration as the logical stage after migrants have earned sufficient assets and knowledge ...
de Haas H, Fokkema T, Fihri MF.
europepmc   +6 more sources

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