Results 131 to 140 of about 143,861 (341)

Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention

Animal Models and Experimental Medicine, EarlyView.
This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie, Hong Zou, Lijing Gong, Minghui Lin, Caihua Huang   +4 more
wiley   +1 more source

Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice

Annals of Neurology, EarlyView.
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi, John Williamson, Huayu Sun, Suchitra Joshi, Rachel Jane Spera, Savaira Zaib, Supriya Sharma, Chengsan Sun, Andrey Brodovskiy, Ifrah Zawar, Jaideep Kapur   +10 more
wiley   +1 more source

Early prehospital mechanical cardiopulmonary resuscitation use for out-of-hospital cardiac arrest: an observational study

BMC Emergency Medicine
Background The use of mechanical cardiopulmonary resuscitation device has been very prevalent in out-of-hospital cardiac arrest rescue. This study aimed to investigate whether the timing of mechanical cardiopulmonary resuscitation device set-up ...
Ying-Kuo Liu, Liang-Fu Chen, Szu-Wei Huang, Shih-Chan Hsu, Chin-Wang Hsu, Jen-Tang Sun, Shu-Hui Chang   +6 more
doaj   +1 more source

Comment on Grmec et al.: A treatment protocol including vasopressin and hydroxyethyl starch solution is associated with increased rate of return of spontaneous circulation in blunt trauma patients with pulseless electrical activity [PDF]

, 2009
Dee Kotak
openalex   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Solar Dynamics, Rotation, Convection and Overshoot

, 2015
We discuss recent observational, theoretical and modeling progress made in understanding the Sun's internal dynamics, including its rotation, meridional flow, convection and overshoot.
Hanasoge, S., Miesch, M. S., Roth, M., Schou, J., Schuessler, M., Thompson, M. J.   +5 more
core   +1 more source

Development and Validation of an Interpretable Prehospital Return of Spontaneous Circulation (P-ROSC) Score for Out-of-Hospital Cardiac Arrest Patients Using Machine Learning

, 2022
Nan Liu, Mingxuan Liu, Xinru Chen, Yilin Ning, Jin Wee Lee, Fahad Javaid Siddiqui, Seyed Ehsan Saffari, Andrew Fu Wah Ho, Sang Do Shin, Matthew Huei‐Ming, Hideharu Tanaka, Marcus Eng Hock Ong   +11 more
openalex   +1 more source

Association of time to return of spontaneous circulation with hemodynamics in comatose survivors of out-of-hospital cardiac arrest [PDF]

, 2023
Frederik T. Søndergaard, Rasmus Paulin Beske, J E Moeller, J Kjaergaard, Henning Schmidt, Johannes Grand, Christian Hassager   +6 more
openalex   +1 more source

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Prediction of Neurological Outcomes in Out-of-hospital Cardiac Arrest Survivors Immediately after Return of Spontaneous Circulation: Ensemble Technique with Four Machine Learning Models

, 2021
Ji Han Heo, Taegyun Kim, Jonghwan Shin, Gil Joon Suh, Joonghee Kim, Yoon Sun Jung, Seung Min Park, Sungwan Kim, For SNU CARE investigators   +8 more
openalex   +1 more source