Results 261 to 270 of about 121,135 (301)

Nitrite supplementation alleviates cerebrovascular dysfunction in chronically stressed mice, but cognitive decline remains

Experimental Physiology, EarlyView.
Abstract This study aimed to determine whether sodium nitrite supplementation prevented chronic stress‐induced cerebrovascular dysfunction and cognitive decline. We hypothesize that nitrite supplementation will prevent the oxidative environment and cerebrovascular dysfunction associated with chronic stress and maintain cognitive health.
Emily Burrage, Tyler Coblentz, Saina S. Prabhu, Nicole M. Eminhizer, Ryan Childers, Randall W. Bryner, Sara E. Lewis, Brooke A. Maxwell, Evan R. DeVallance, Eric E. Kelley, Paul D. Chantler   +10 more
wiley   +1 more source

Establishment of a mouse model for ischaemic heart failure induced by coronary microembolization via left ventricular oil injection

Experimental Physiology, EarlyView.
Abstract Over the past three decades, there has been a steady increase in clinical attention to ischaemic heart failure caused by coronary microembolization. Nonetheless, a suitable mouse model for studying this condition remains limited. In the present study, we developed a mouse model of coronary microembolization‐induced ischaemic heart failure by ...
Lang Pei, Yusheng Hong, Qiuyue Wu, Jianyi Lv, Changlong Li, Xueyun Huo, Xin Liu, Di Zhang, Meng Guo, Zhenwen Chen, Xiaoyan Du   +10 more
wiley   +1 more source

Optimizing cerebrovascular endothelial health through shear stress modulation

Experimental Physiology, EarlyView.
Abstract The endothelium plays a pivotal role in regulating cerebrovascular blood flow, and its dysfunction increases the risk of cerebrovascular disease. Endothelial shear stress, a primary mechanical stimulus for endothelial nitric oxide production, is a key modulator of vascular adaptation.
Erika Iwamoto, Rintaro Sakamoto, Darren P. Casey   +2 more
wiley   +1 more source

Association between minute ventilation, ventilation volume, ventilation rate, and return of spontaneous circulation in non-traumatic cardiac arrest patients

Kanokwan Sukeewong, Wasin Pansiritanachot, Sattha Riyapan, Tipa Chakorn, Apichaya Munsomboon, Tanyaporn Nakornchai, Wansiri Chaisirin   +6 more
openalex   +1 more source

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Sustained Return of Spontaneous Circulation Following Out-of-Hospital Cardiac Arrest; Developing a Predictive Model Based on Multivariate Analysis

Archives of Academic Emergency Medicine, 2023
Introduction: Identifying the predictive factors of sustained return of spontaneous circulation (ROSC) following out-of-hospital cardiac arrest (OHCA) will be helpful in management of these patients. This study aimed to develop a predictive model in this
Thongpitak Huabbangyang, Agasak Silakoon, Pramote Papukdee, Rossakorn Klaiangthong, Chaleamlap Thongpean, Wannakorn Pralomcharoensuk, Weerawan Khaokaen, Sunisa Bumrongchai, Ratree Chaisorn, Chomkamol Saumok   +9 more
semanticscholar   +1 more source

Trends in Return of Spontaneous Circulation and Survival to Hospital Discharge for In-Intensive Care Unit Cardiac Arrests.

Annals of the American Thoracic Society, 2023
RATIONALE Nearly 3 in 5 in-hospital cardiac arrests occur in the ICU, yet large scale data on the outcomes of in-ICU cardiac arrests have not been published for over a decade. OBJECTIVE We sought to examine outcomes of in-ICU cardiac arrests evaluating
L. Cagino, A. Moskowitz, B. Nallamothu, J. McSparron, T. Iwashyna   +4 more
semanticscholar   +1 more source

Time to Antiarrhythmic and Association with Return of Spontaneous Circulation in the United States

Prehospital Emergency Care, 2022
Introduction Recent clinical trials have failed to identify a benefit of antiarrhythmic administration during cardiac arrest. However, little is known regarding the time to administration of antiarrhythmic drugs in clinical practice or its impact on ...
Ryan M. Huebinger, H. Chan, B. Bobrow, Summer Chavez, Kevin Schulz, Richard Gordon, J. Jarvis   +6 more
semanticscholar   +1 more source

Prehospital predictors for return of spontaneous circulation in traumatic cardiac arrest

Journal of Trauma and Acute Care Surgery, 2021
Not-asystolic rhythms, spontaneous activity, gasping, ALS interventions (intravenous fluid resuscitation, packed red cells transfusion, external haemorrhage control) are associated with sustained return of spontaneous circulation in a national French ...
A. Benhamed, Valentine Canon, É. Mercier, M. Heidet, Amaury Gossiome, D. Savary, C. El Khoury, P. Gueugniaud, H. Hubert, K. Tazarourte   +9 more
semanticscholar   +1 more source

The Effect of Prearrest Acid-Base Status on Response to Sodium Bicarbonate and Achievement of Return of Spontaneous Circulation

The Annals of Pharmacotherapy, 2021
Background The efficacy of sodium bicarbonate (SB) administration during in-hospital cardiac arrest (IHCA) for treatment of acidosis is not well described.
Heath Mclean, L. Wells, Jacob Marler
semanticscholar   +1 more source

Hyperoxia After Return of Spontaneous Circulation in Cardiac Arrest Patients.

Journal of Cardiothoracic and Vascular Anesthesia, 2021
Current guidelines emphasize the use of 100% oxygen during cardiopulmonary resuscitation after cardiac arrest. When patients are ventilated for variable periods after return of spontaneous circulation (ROSC), hyperoxia causes increased morbidity and ...
R. Latif, S. Clifford, Keith R Byrne, B. Maggard, Yaruk Chowhan, Jawad Saleem, Jiapeng Huang   +6 more
semanticscholar   +1 more source