Results 201 to 210 of about 33,030 (277)

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Maps of forest vertical structure for Colombia, a megadiverse country. [PDF]

Sci Data
Camilo Fagua J, Jantz P, Burns P, Jantz SM, Kilbride JB, Goetz SJ.   +5 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Can data assetization drive high-quality enterprise development?-Evidence from China's "Specialized, refined, unique, and innovative" SMEs. [PDF]

PLoS One
Li L, Zhu J.
europepmc   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

Advanced Science, EarlyView.
ABSTRACT The cytosine (C) modifications 5‐methylcytosine (mC) and 5‐hydroxymethylcytosine (hmC) are central regulatory elements of mammalian genomes. Both marks occur in double‐stranded DNA in either strand‐symmetric or ‐asymmetric fashion, but it is still poorly understood how this symmetry information is selectively read out by the nuclear proteome ...
Lena Engelhard, Zeyneb Vildan Cakil, Marlon S. Zambrano‐Mila, Simone Eppmann, Tye Gonzalez, Rasmus Linser, Petra Janning, Sidney Becker, Daniel Summerer   +8 more
wiley   +1 more source

The Effect of Return on Equity, Dividend Payout Ratio, and Debt to Asset Ratio on Retail Investor Investment Decisions

Kimsen Kimsen, Irwan Irawadi Barus, Djauhar Edi Purnomo, Rina Malahayati, Eko Sudarmanto   +4 more
openalex   +2 more sources

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source

The impact of banking uncertainty on firm investment: A look into intangible assets. [PDF]

PLoS One
Huynh J, Phan TMH.
europepmc   +1 more source

Pengaruh Struktur Aktiva (Fixed Asset Ratio), Profitability (Return On Asset) dan Ukuran Perusahaan terhadap Struktur Modal (Debt Equity Ratio) di Bursa Efek Indonesia Tahun 2020 – 2023

Fastami’ Lima Yukha, Erna Puspita, Diah Nurdiwaty   +2 more
openalex   +2 more sources

Pneumatically‐Actuated Liquid Metal‐Based Frequency Reconfigurable Antenna

Advanced Science, EarlyView.
A look at a flexible, frequency‐tuning antenna A Soft Solution: Introducing a new antenna design made with liquid metal composites. A Full Package: Combining flexible antennas with pneumatic actuators. End‐to‐End Control: Automatic reconfiguration according to signal strength.
Yiwen Song, Aditya Bharambe, Dinesh K. Patel, Barbara Zhuo, Mason Zadan, Carmel Majidi, Swarun Kumar   +6 more
wiley   +1 more source