Results 281 to 290 of about 2,832,843 (380)
A study of hybrid deep learning model for stock asset management. [PDF]
Huo Y, Jin M, You S.
europepmc +1 more source
Targeting p21‐Positive Senescent Chondrocytes via IL‐6R/JAK2 Inhibition to Alleviate Osteoarthritis
This study uncovers a novel mechanism behind uneven cartilage degeneration in knee osteoarthritis (OA). Elevated IL‐6R expression activates the IL‐6 pathway, leading to SIRT1 degradation, chondrocyte senescence, and reduced SOX9 activity, which impairs cartilage matrix synthesis. Notably, the JAK inhibitor tofacitinib prevents IL‐6R‐mediated senescence,
Xiang Zhao+11 more
wiley +1 more source
Risk preference and rural livelihood transitions in the hilly and mountainous region of southern China: a case study in Ruijin City. [PDF]
Wu Z, Chen H, Zeng T, Yan Y, Zhang M.
europepmc +1 more source
NF2 is Essential for Human Endoderm Development
This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong+5 more
wiley +1 more source
Income diversification and liquidity risk in ASEAN-5 banks: A Bayesian perspective. [PDF]
Duong QN, Tran NTK, Dang TPT.
europepmc +1 more source
With emphasis on a diabetic state, this study highlights the role of mesenchymal stem cells (MSCs) in enhancing vascularization and modulating immune responses within a subcutaneous platform for cell transplantation for type 1 diabetes (T1D). Comprehensive profiling of MSC‐induced angiogenic and immune responses, provides insight into the role of MSCs ...
Jocelyn Nikita Campa‐Carranza+19 more
wiley +1 more source
Nonlinear connectedness of conventional crypto-assets and sustainable crypto-assets with climate change: A complex systems modelling approach. [PDF]
Khan MH, Macherla S, Anupam A.
europepmc +1 more source