Fouling‐Free Inertial Microfluidic Cell Clarification for Lentivirus Manufacturing
ABSTRACT Lentiviral vectors (LVVs) are widely used as gene‐delivery vehicles in cell and gene therapy, enabling stable integration of transgenes into target cells. However, efficient clarification of LVV harvest remains a major bottleneck in large‐scale manufacturing, as conventional depth filtration often results in significant product loss.
Dohyun Park +5 more
wiley +1 more source
The need of innovation and of preservation of well-established techniques in the era of MDR for improving outcomes. [PDF]
Gordon M, Wolf O, Mili-Schmidt V.
europepmc +1 more source
Real‐Time Biomass Estimation in High‐Density Yeast Fermentations Using Soft Sensor Modeling
Accurate biomass measurements, both offline and online, are essential to improve prediction and control in yeast fermentation. This study develops regression‐based predictive models to correlate offline measurements (Dry Cell Weight and OD600 from a spectrophotometer) with online OD860 probe signals to provide accurate real‐time biomass estimations and
Ana G. Del Hierro +3 more
wiley +1 more source
Adaptive Compressed Sensing Differential Privacy Federated Learning Based on Orbital Spatiotemporal Characteristics in Space-Air-Ground Networks. [PDF]
Li W, Li L, Zhu L.
europepmc +1 more source
Spatial metrics in fire ecology: seeking consistency amidst complexity
ABSTRACT Technological advances, including remote sensing, have led to a proliferation of metrics used in ecological studies to examine spatial patterns of fire regimes and their ecological effects. Researchers can use many different metrics to analyse spatial variation in both fire events and resulting fire regimes, including fire size, shape ...
Alexander R. Carey +5 more
wiley +1 more source
TARFA: A Novel Approach to Targeted Accounting Range Factor Analysis for Asset Allocation. [PDF]
de Leon JJ, Medda F.
europepmc +1 more source
The influence of rivers on seabird foraging ecology
ABSTRACT Rivers act as vital arteries to the world's oceans, delivering fresh water and nutrients that sustain marine ecosystems. Globally, river flow increasingly is being altered by climate change and anthropogenic pressures; yet the significance of rivers to predatory marine species, such as seabirds, and the extent to which river‐related changes ...
Julia B. Morais +2 more
wiley +1 more source
A large-effect locus underlies migration timing in North American Atlantic salmon (Salmo salar). [PDF]
Beck SV +9 more
europepmc +1 more source
Extent, characteristics and policy applications of Key Biodiversity Areas
ABSTRACT A global standard for the identification of Key Biodiversity Areas (KBAs) was published 10 years ago to provide a unified set of criteria for identifying ‘sites of significance for the global persistence of biodiversity’. We review the initiative's origins, the KBA identification process, characteristics of the current network, threats, policy
Stuart H. M. Butchart +57 more
wiley +1 more source
Promoting sustainable human mobility for income segregation mitigation. [PDF]
Chen Y +7 more
europepmc +1 more source

