Results 61 to 70 of about 226,168 (262)

Microenvironment‐Responsive Nanomedicine Enables Vertical Modulation of Mitochondrial Pathological Networks in Myocardial Ischemia–Reperfusion Injury

Advanced Science, EarlyView.
A mitochondria‐targeted, microenvironment‐responsive nanoplatform enables pH/ROS‐triggered co‐delivery of berberine and isoliensinine to orchestrate ROS scavenging, inflammation suppression, and apoptosis inhibition. This vertical modulation of mitochondrial pathological networks preserves mitochondrial function and effectively mitigates myocardial ...
Jue Wang, Jia Zhou, Wenqin Yuan, Tianjiao Zhao, Yunying Huang, Yingci Xia, Yuting Lin, Fei Li, Qiong Huang, Chong Liu, Kelong Ai, Qun Qin   +11 more
wiley   +1 more source

Incidence, Predictors, and Outcomes of Complete Angina Relief in Symptomatic Patients in the ISCHEMIA Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Patients with chronic coronary disease experience less angina with revascularization plus optimal medical therapy compared with optimal medical therapy alone.
Ayesha Singh, Jack C. S. Rodman, David L. Brown   +2 more
doaj   +1 more source

Oral Delivery Systems for Food‐Derived Bioactive Peptides: Enhancing Stability, Bioavailability, and Health Benefits

Advanced Science, EarlyView.
Advanced delivery systems—including nanoparticles, nanoemulsions, liposomes, and hydrogels—protect food‐derived bioactive peptides from gastrointestinal degradation and bitterness. These systems enable pH‐responsive release, enhance intestinal absorption, and improve therapeutic efficacy against oxidative stress, metabolic disorders, cancer, and ...
Yu Xu, Fan Li, Runan Zhao, Tao Shu, Weihong Min, Bei‐Wei Zhu   +5 more
wiley   +1 more source

Iliac Calcium Score thresholds predict cardiovascular and limb-related outcomes in TASC D aortoiliac disease

Frontiers in Medicine
IntroductionExtensive lower limb arterial calcification complicates revascularization and is linked to poor outcomes, including limb loss and cardiovascular events.
António Pereira-Neves, António Pereira-Neves, João Rocha-Neves, João Rocha-Neves, João Rocha-Neves, Tiago Costa-Pereira, Tiago Costa-Pereira, Hugo Ribeiro, Hugo Ribeiro, Hugo Ribeiro, Hugo Ribeiro, Lara R. Dias, Lara R. Dias, Luís Duarte-Gamas, José P. Andrade, José P. Andrade   +15 more
doaj   +1 more source

Case of successful hybrid revascularization and limb salvage in patient with CLI after multiply ABF thrombosis and absence of outflow arteries

Атеротромбоз, 2020
Patients with CLI often present multilevel disease. They underwent multiply revascularization procedures aiming to save thelimb. The main obstacle is absence or poor outflow arteries.
A. F. Kharazov, V. M. Luchkin, N. M. Basirova, V. A. Kulbak, A. I. Maslov   +4 more
doaj   +1 more source

Mortality After Repeat Revascularization Following PCI or Coronary Artery Bypass Grafting for Left Main Disease: The EXCEL Trial.

JACC: Cardiovascular Interventions, 2020
OBJECTIVES The aim of this study was to investigate the incidence and impact on mortality of repeat revascularization after index percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) for left main coronary artery disease ...
G. Giustino, P. Serruys, J. Sabik, R. Mehran, A. Maehara, J. Puskas, C. Simonton, N. Lembo, D. Kandzari, M. Morice, D. Taggart, A. Gershlick, M. Ragosta, I. Kron, Yangbo Liu, Zixuan Zhang, T. McAndrew, O. Dressler, P. Généreux, O. Ben-Yehuda, S. Pocock, A. Kappetein, G. Stone   +22 more
semanticscholar   +1 more source

Rocket‐Inspired Sequentially Targeted Nanotherapeutics for Mitochondrial Regulation and Inflammatory Reprogramming in Ischemic Stroke

Advanced Science, EarlyView.
A novel neutrophil‐hitchhiking, rocket‐inspired nanoplatform is developed to cross the blood‐brain barrier for sequential, spatiotemporal drug delivery. By responsive surface transformation in the ischemic penumbra, it precisely targets mitochondria to suppress Drp1‐mediated fission.
He Bai, Zihao Yong, Yang Li, Qingmin Chen, Yong Liu, Xiaomeng Guo, Fukai Li, Shicheng Tang, Zhuo Yang, Yufei Zhang, Ruwei Jie, Xiaohong Lv, Huacheng Wang, Chunming Huang, Liwei Xie, Jianqi Xiao, Qingchun Mu, Longguang Tang   +17 more
wiley   +1 more source

Impact of multivessel versus single-vessel disease on the association between low diastolic blood pressure and mortality after acute myocardial infarction with revascularization

Cardiology Journal
BACKGROUND: Previous studies demonstrated a J-shaped relationship between low diastolic blood pressure (DBP) and adverse clinical outcomes in patients with acute myocardial infarction (AMI) that was sensitive to revascularization.
Min Kim, Dae-Hwan Bae, Ju Hee Lee, Dae In Lee, Sang Min Kim, Sang Yeub Lee, Jang-Whan Bae, Dong-Woon Kim, Myeong-Chan Cho, Jin Yong Hwang, Seok Kyu Oh, Kwang Soo Cha, Cheol Ung Choi, Hyeon Cheol Gwon, Myung Ho Jeong, Kyung-Kuk Hwang   +15 more
doaj   +1 more source

The Risk of Cardiovascular Diseases for Shift Workers in the Prospective Heinz Nixdorf Recall Study

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Shift work can disrupt circadian rhythms and is postulated to play a role in cardiovascular diseases (CVD). In the German prospective population‐based Heinz Nixdorf Recall Study, we analyzed longitudinal associations between shift work and night‐shift work with CVD.
Katharina Wichert, Sylvia Rabstein, Raimund Erbel, Lewin Eisele, Marina Arendt, Nico Dragano, Karl‐Heinz Jöckel, Thomas Behrens   +7 more
wiley   +1 more source

Intraoperative graft patency validation: Friend or foe?Central Message

JTCVS Techniques, 2021
Rami Akhrass, MD, Faisal G. Bakaeen, MD
doaj   +1 more source