Results 101 to 110 of about 88,437 (294)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
St Andrews Encyclopaedia of TheologyHermeneutical theology is an approach to theological inquiry arising from the work of Karl Barth and Rudolf Bultmann around the midpoint of the twentieth century. The movement materialized in the works of Gerhard Ebeling, Ernst Fuchs, and Eberhard Jüngel
C. M. Howell
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Aural/Oral Histories of Pain and Trust in Satoshi Miyagi’s Révélation
Critical Stages, 2021 Our essay analyzes Satoshi Miyagi’s production of Révélation, written by the Cameroon-born dramatist Léonora Miano, translated into Japanese by Akihito Hirano and staged first at La Colline—Théâtre national, Paris, in August 2018, and then in Shizuoka ...
Tomoka Tsukamoto, Ted Motohashi
doaj
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Eyes to see and ears to hear: Discernment of revelation in the gospel of Mark [PDF]
, 1993 The biblical tradition affirms that God reveals himself, but also that such revelation is hidden and diverse, surprising and paradoxical. The aim of this study is to examine how Mark understands revelation to be given and discerned.
Shaw, Frances
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Reason and Revelation in Malebranche and Locke
, 2021 My paper deals with the question of the relationship between reason and revelation in Malebranche and Locke. First of all, I would like to examine Malebranche’s position.
Raffaele Carbone
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