Results 141 to 150 of about 67,981 (313)

The Problem of Revelation and Philosophizing in Gaudiya Vedanta

open access: yesИнтеллект. Инновации. Инвестиции
The research is aimed at the historical and philosophical reconstruction of the problems of Gaudiya Vedanta theory of knowledge related to philosophizing, the concept of revelation and qualification (adhīkāra), in the philosophy of India of XVI–XX ...
D. N. Popov
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Communion of the living and the dead: valuing purgatory in A revelation of purgatory to ane holy woman (1422)

open access: yes, 2009
Revelation of Purgatory to Ane Holy Woman (1422) is one of only five extant fifteenth-century visions of Purgatory written in England. The text addresses the anxiety prevalent in the late Middle Ages that the dead in Purgatory are often forgotten by the ...
Bayne-Jardine, Michelle Lisa
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

History, Holocaust, and Revelation

open access: yes, 2005
This article explores the still-unresolved question surrounding the relationship of history to theology, specifically the role of traumatic history in the formulation of theological discourse.
Mark R. Lindsay
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Isaiah 1:2−3 and Isaiah 6: Isaiah ‘a prophet like Moses’ (Dt 18:18)

open access: yesHTS Teologiese Studies/Theological Studies, 2012
The book of Isaiah is complex when one considers the reconstruction of the processes of its formation and transmission. If these complexities are examined more closely, it is apparent that there is a multiplicity of dimensions to the book.
Alphonso Groenewald
doaj  

Theological Affinities Between the Fourth Gospel and the Book of Revelation

open access: yesPerichoresis: The Theological Journal of Emanuel University
The focus of this study is on the exploration of theological affinities between the Fourth Gospel and Revelation. While I personally hold to the apostolic authorship of both writings by John, the son of Zebedee — admittedly a minority view in ...
Köstenberger Andreas J.
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

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