Results 221 to 230 of about 1,594,454 (293)
Entrepreneurship Under Fire: Psychological Distress During Armed Conflict from a Public Health Perspective. [PDF]
Hadad S, Shaked O.
europepmc +1 more source
Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu +14 more
wiley +1 more source
Crop rotations synergize yield, nutrition, and revenue: a meta-analysis. [PDF]
Mudare S +9 more
europepmc +1 more source
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang +15 more
wiley +1 more source
Tracking business opportunities for climate solutions using AI in regulated accounting reports. [PDF]
Lu S, Serafeim G, Xu S, Awada M.
europepmc +1 more source
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An +8 more
wiley +1 more source
Financing pathways for the ageing industry: mitigating risks in older adult care investment. [PDF]
Na L, Zesheng L, Tong P.
europepmc +1 more source
Impact of FDI on tax revenue in Pakistan
Haider Mahmood, A. R. Chaudhary
openalex +1 more source
Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai +13 more
wiley +1 more source

