Results 41 to 50 of about 300,105 (313)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

PENGARUH RATING DAN ONLINE CONSUMER REVIEW TERHADAP MINAT BELI DENGAN KEPERCAYAAN SEBAGAI PEMEDIASI PADA MARKETPLACESHOPEE DALAM PERSFEKTIF EKONOMI ISLAM (Studi pada Mahasiswa Universitas Islam Negeri Raden Intan Lampung)

open access: yesRevenue, 2021
Seiring dengan perkembangan zaman, teknologi dan informasi didunia khususnya internet mengalami perkembangan yang sangat pesat. Perkembangan internet di Indonesia juga telah mempengaruhi stabilitas ekonomi.
Tiara Ramadhani, VIcky F Sanjaya
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

STRATEGI PEMASARAN AYAM KAMPUNG DI BANDAR LAMPUNG

open access: yesRevenue, 2021
Peternakan merupakan suatu kegiatan yang mengembangbiakkan dan membudidayakan hewan ternak untuk mendapatkan manfaat dan hasil dari kegiatan tersebut.
Selfi Alhuda
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

PENGARUH PENGGUNAAN SISTEM PEMBAYARAN SHOPEEPAYLATER “BAYAR NANTI” TERHADAP PERILAKU KONSUMTIF MAHASISWA UIN RADEN INTAN LAMPUNG DALAM PERSPEKTIF BISNIS SYARIAH

open access: yesRevenue, 2022
ShopeePayLater adalah jasa yang diberikan oleh Shopee kepada pengguna untuk mendapatkan produk terlebih dahulu namun pembayaran dapat dilakukan pada awal bulan berikutnya.
Sonia Aftika, Hanif Hanif, Yulistia Devi
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Analisis Perbandingan Pengaruh Instrumen Moneter Syariah Dan Konvensional Terhadap Penyaluran Dana Ke Sektor Properti Di Indonesia Periode 2014-2020

open access: yesRevenue, 2022
Penelitian ini bertujuan untuk menganalis perbandingan pengaruh instrumen moneter syariah dan konvensional terhadap penyaluran dana ke sektor properti melalui perbankan syariah dan konvensional dari Januari 2014 hingga September 2020 dengan menggunakan ...
Tiara Nirmala, Riska Aperta Putri
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

SELFIE BEHAVIOR.THE MODERATING ROLE OF PERSONALITY

open access: yesRevenue, 2020
This study aimed to investigate the effect of selfie behavior to individual performance with extrovert personality as a moderating variable. Inconsistence result of the past research on narcissism topic is a uniqueness gap for this research.
Leonilan Leonilan   +2 more
doaj   +1 more source

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