Results 61 to 70 of about 6,616 (298)

Funding diversification, governance autonomy, and higher education resilience

open access: yesInternational Review of Economics & Finance
This paper examines whether funding diversification enhances higher education resilience under fiscal uncertainty. Using panel data on universities from 2010 to 2023, we construct a composite resilience index capturing institutional stability, adaptive ...
Zheng ShaoXin, Li Ming
doaj   +1 more source

PGK1 Suppresses CD8+ T Cell‐Mediated Antitumor Immunity Through CCL2/CCR2/Tumor‐Associated Macrophages Axis in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
PGK1 in tumor cells upregulates CCL2 expression through activation of the AKT/GSK‐3β/β‐catenin signaling axis, thereby promoting the recruitment and M2 polarization of TAMs and ultimately impairing the infiltration and activation of CD8+ T cells within the HCC tumor microenvironment. ABSTRACT Patients with advanced hepatocellular carcinoma (HCC) have a
Xi Liu   +17 more
wiley   +1 more source

FINANCIAL SUSTAINABILITY OF BULGARIAN FOOTBALL: A BALKAN PERSPECTIVE

open access: yesTrakia Journal of Sciences
Purpose: This study examines the financial performance and sustainability of Bulgarian professional football clubs compared to other Balkan countries, focusing on revenue diversification, UEFA income, and infrastructure ...
D. Ivanov
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

open access: yesAdvanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai   +7 more
wiley   +1 more source

Government Revenue Volatility in Alberta [PDF]

open access: yes
The Alberta government is heavily exposed to energy price volatility as it relies to a great extent on revenue derived from the production of oil and natural gas. Energy prices change substantially and unpredictably, causing large and uncertain movements
Landon, Stuart, Smith, Constance
core  

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan   +11 more
wiley   +1 more source

Diversification and banks’ funding costs in Africa: The role of financial regulations

open access: yesSouth African Journal of Economic and Management Sciences
Background: The banking literature suggests that banks can reduce their funding costs by optimising their deposit mix to prioritise low-cost accounts, managing capital efficiently, and employing diversification strategies to attract more cost-effective ...
Simon Kamau, Beatrice D. Simo-Kengne
doaj   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

open access: yesAdvanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu   +9 more
wiley   +1 more source

Fiscal revenue mobilization and structural transformation in Sub-Saharan Africa: a panel data analysis

open access: yesCogent Economics & Finance
Achieving structural transformation is central to the Sustainable Development Goals, particularly those related to sustained economic growth, decent work, and reduced inequalities, yet Sub-Saharan Africa continues to grapple with weak diversification and
Augustin Chola Kazembe   +3 more
doaj   +1 more source

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