Results 261 to 270 of about 22,819,678 (341)

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

Advanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng, Jia‐Jia Liang, Yun‐Feng Zhan, Wei‐Xun Wu, Wan‐Li Xu, Xiao‐Kun Zhang, Li‐Jun Cai, Fu‐Quan Jiang   +7 more
wiley   +1 more source

The Receding Specialty of Infectious Diseases and Implications for U.S. Healthcare. [PDF]

Open Forum Infect Dis
Bearman G, Mullin R, Nori P.
europepmc   +1 more source

MDP25‐VDAC3 Complex Orchestrates Actin Remodeling and Mitochondrial Dynamics to Modulate Innate Immunity in Arabidopsis

Advanced Science, EarlyView.
This study reveals that actin remodeling regulates mitochondrial elongation as a defense strategy in plants. Flagellin perception induces fusion‐dependent elongation, supported by cortical actin bundles, to repair damage and boost ATP and ROS production.
Junxiu Hou, Pengfei Lu, Xuan Cui, Liangfeng Luo, Qing Pan, Jiejie Li   +5 more
wiley   +1 more source

Bridging the fair share gap for antibacterial innovation: an observational analysis of antibacterial revenues in the G7 and EU27. [PDF]

EClinicalMedicine
Goh M, McEnany M, Freeman R, Newton M, Kesselheim AS, Outterson K.   +5 more
europepmc   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Global market trends and financial performance of the corporate fast-food industry and their potential contributions to diets high in meat and ultra-processed foods. [PDF]

Global Health
Sievert K, Botha T, Wood B, Baker P, Scapin T, Sacks G.   +5 more
europepmc   +1 more source

The Evolution of Automated Medical Billing With Artificial Intelligence: A Review With a Global and Saudi Perspective. [PDF]

Cureus
Nasser LK.
europepmc   +1 more source

Generative AI costs in large healthcare systems, an example in revenue cycle. [PDF]

NPJ Digit Med
Burns ML, Chen SY, Tsai CA, Vandervest J, Pandian B, Nong P, Hanauer DA, Rosenberg A, Platt J.   +8 more
europepmc   +1 more source

Experiences With Maryland's All-Payer Model Among Surgeons.

JAMA Netw Open
Shammas RL, Fish LJ, Petrillo LA, Falkovic M, Makarushka C, Parnell H, Jain A, Slezak SS, Giladi AM, Mehrara BJ, Keating NL, Matros E, Aliu O, Offodile AC.   +13 more
europepmc   +1 more source

Evolutionary game analysis of supply chain financing for film and television enterprises considering co-production. [PDF]

PLoS One
Zhen Y, Li H, Wang W.
europepmc   +1 more source