Results 191 to 200 of about 452,472 (312)

Fiscal federalism, inter-governmental transfers and public health- The case of Urban Local Bodies in India.

SSM Health Syst
Chowdhury S.
europepmc   +1 more source

Context matters: A meta-ethnography investigating barriers and facilitators for the effective implementation of gambling harm prevention and reduction policies. [PDF]

PLoS One
Selin J, Kauppila L.
europepmc   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Reinforcing the value of statewide trauma systems. [PDF]

Trauma Surg Acute Care Open
Gannon JE, Covey Van Winkle B, Conaway E.   +2 more
europepmc   +1 more source

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li, Li Chen, Tao Wang, Haiyang Jiang, Huijuan Wang, Mengyu Li, Guanpeng Xie, Chunhua Xi, Han Yan, Chunhui Lu, Chenchen Li, Hanyu Zhu, Feihu Sun, Lingdi Yin, Jun Yu, Yi Miao   +15 more
wiley   +1 more source

Impact of the Eras Protocols on Costs and Benefits in Two Italian Second-Level Healthcare Centers According to the National Waiting List Management Plan (PNGLA). [PDF]

J Clin Med
Frattini F, Fabbi M, Bardelli L, Galli F, Iovino D, Liepa L, Milani MS, Pappalardo V, Pavesi F, Surace M, Donnini L, Baù D, Poggialini G, Covacich P, Isella L, Rausei S.   +15 more
europepmc   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Eradication of commercial tobacco related disease and death. [PDF]

Tob Control
Maddox R, Telford RM, Waa A, Diaz A, Bradbrook SK, Calma T, Whop LJ.   +6 more
europepmc   +1 more source

Recognition Of Contract Revenues And Expenses

Annales Universitatis Apulensis Series Oeconomica, 2007
openaire   +1 more source

Federal Income Tax: Involuntary Conversions as Section 337 Sales or Exchanges [PDF]

, 1961
Skilström, Erika
core   +1 more source