Results 101 to 110 of about 824,283 (335)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

The government’s new Digital Economy Act will do little to prevent file sharing – the music industry must continue to innovate online if it is to survive [PDF]

open access: yes, 2011
Nearly as old as the internet, the peer-to-peer file sharing of music online has been a constant bugbear for the music industry, with claims of billions in lost revenues over the past decade. Bart Cammaerts and Bingchun Meng have found that despite these
Cammaerts, Bart, Meng, Bingchun
core  

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Smoke-free law did affect revenue from gaming in Delaware [PDF]

open access: yes
A paper recently published in the journal Tobacco Control purports to show that the implementation of a smoking prohibition in Delaware had no statistically significant effect on the revenues of three gaming facilities in that state. After correcting for
Michael R. Pakko
core  

Financial Distress and Its Determinants in Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent prolonged use of expensive disease‐modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or noninflammatory musculoskeletal disease (NIMSKD) completing the ...
Amber Brown Keebler   +5 more
wiley   +1 more source

A Corpus-Based Study of the Discourse of Recreational Marijuana Legalization

open access: yesCorporum, 2022
Recreational Marijuana Legalization (RML) is strongly supported in business, legal, and political circles, but opposed mostly by the medical professions.
Susana Sotillo
doaj  

ANCILLARY REVENUE PRICING

open access: yesJournal of Air Transport Studies, 2015
The airline industry has evolved from a system of long-established state owned carriers operating in a regular market to a dynamic, deregulated industry. This development – especially the emerging competition of low-cost carriers – has had a major influence on the price setting behaviour of airlines.
Wittmer, Andreas, Oberlin, Nicole
openaire   +3 more sources

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie   +3 more
wiley   +1 more source

Whole-Farm Revenue Protection as a Factor of Economic Stability in Crop Production [PDF]

open access: gold, 2020
Željko Kokot   +3 more
openalex   +1 more source

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