Results 281 to 290 of about 824,283 (335)

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Universal health coverage in Lebanon: agenda setting using Kingdon's model and a proposed legal framework for revenue allocation. [PDF]

Front Health Serv
Mouawad J, Lteif MR, Mina W, Karam R.
europepmc   +1 more source

A critical analysis of the principles relating to simulated transactions in the context of the case of commissioner for the South African revenue services v NWYK limited 73 SATC 55

, 2014
Heinrich Louw
openalex   +1 more source

Dataset for the article "Potential overinterpretation of results in the abstracts of machine learning studies for movie box office revenue prediction: a systematic review"

Joerg Leukel
openalex   +1 more source

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

Advanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

The impact of various forms of non-alcoholic beverage taxation on sales of non-alcoholic beverages and sugar in the Netherlands: a modelling study. [PDF]

BMC Public Health
Eykelenboom M, Oosterhoff M, Milder IEJ, van Giessen A.   +3 more
europepmc   +1 more source

Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase

Advanced Science, EarlyView.
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo, Subramanya Hegde, Xuan Jia, Kimberly Coffman, Hariprasad Vankayalapati, David Bearss, Kevin B. Jones, Alex W. Stark, Peter S. Shen   +8 more
wiley   +1 more source

Negative Electric Vehicle Emissions: Vehicle-to-Grid Can Incentivize Enough Wind and Solar Investment to Reverse EV Charging Emissions. [PDF]

Environ Sci Technol
Chen J, Craig MT, Michalek J, Bruchon M, Vaishnav P.   +4 more
europepmc   +1 more source

The cost of misaligned incentives in the pharmaceutical supply chain. [PDF]

Health Aff Sch
Joyce G.
europepmc   +1 more source

The new wave of ocean industrialization and the challenges for biodiversity conservation in the Mediterranean Sea: the case of the Costa Brava. [PDF]

Sci Rep
Lloret J, Wawrzynkowski P, Sardá R, Rigall R, Mujal-Colilles A.   +4 more
europepmc   +1 more source