Results 31 to 40 of about 824,283 (335)
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman +17 more
wiley +1 more source
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane +11 more
wiley +1 more source
ANALYSIS OF INCOME, EXPENSES AND PROFIT OF AN AGRICULTURAL ENTERPRISE
The purpose of this study is to determine the degree of efficiency in the production of three main agricultural crops - wheat, corn, and sunflower –through an analysis of income, expenses, and profit.
P. Petkova, H. Momchilov
doaj +1 more source
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt +76 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Water for Forest: Potential impact of alternative land setaside programs at village and farm levels in the mountainous areas of Vietnam [PDF]
The uplands of Northern Vietnam, often having low agricultural productivity, are home to the poorest of the rural poor. The ecosystem services such as food production for marginalized populations, biodiversity reservoirs, and watershed regulating ...
Boere, Esther +5 more
core
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Financial Audit and Spending of Appropriations
Local and district (regional) governments receive various forms of revenue. The entitlement to and purpose of this income is determined by law. Likewise for companies owned by local government there are revenues with allocated use, which are also ...
Ivo Mijoč, Dubravka Mahaček
doaj
Sensitivity of contribution margin in milk production on family farms [PDF]
Milk production in Serbia is characterized by small surface of production and a large number of small family farms. For rural areas where this production is mostly carried out economic profitability of production contributes to becoming a family business.
Biljana Veljkovic +3 more
doaj +1 more source

