Results 211 to 220 of about 97,587 (315)

METTL10‐Mediated PIAS3 Methylation Links Purine Metabolism to Gastric Cancer Progression

open access: yesAdvanced Science, EarlyView.
METTL10‐mediated methylation of PIAS3 at K442 inhibits its SUMO E3 ligase activity toward MITF. This reduces MITF SUMOylation and subsequent RNF4‐mediated ubiquitination, leading to MITF protein accumulation and gastric cancer progression. Abstract Metabolic dysregulation plays a significant role in the development of gastric cancer (GC).
Jinshui Tan   +20 more
wiley   +1 more source

Catalytic Electron‐Driven Non‐Equilibrium Phase Transition in Quantum Electronic Heterostructures

open access: yesAdvanced Science, EarlyView.
This study proposes an innovative method to control the phase of heterostructured materials via electron flow manipulation. Leveraging this technique, a new topological phase is achieved that hosts excitons at the interface of a topological insulator.
Byung Cheol Park   +5 more
wiley   +1 more source

Testing of VoLTE mean opinion score in reverberation chambers

open access: green, 2020
Massimo Barazzetta   +6 more
openalex   +2 more sources

Multimodal Imaging Reveals Cerebral Microcirculation Dynamics and Mechanisms in Mouse Central Nervous System After Intranasal Infection With Recombinant Pseudorabies Virus

open access: yesAdvanced Science, EarlyView.
Multi‐modality imaging strategy applied to PRV‐induced central nervous system infection enables dynamic visualization of cerebrovascular dysfunction, including hyperemia, hypoperfusion, and vascular remodeling. These changes are linked to microglial activation and impaired angiogenesis, providing mechanistic insight into PRV neuropathogenesis and ...
Shuting Ling   +13 more
wiley   +1 more source

Ultrasound Findings of Emphysematous Pyelonephritis: A Case Series. [PDF]

open access: yesJ Am Coll Emerg Physicians Open
Villanueva JC   +5 more
europepmc   +1 more source

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

open access: yesAdvanced Science, EarlyView.
cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang   +14 more
wiley   +1 more source

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