Results 41 to 50 of about 7,593 (278)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

Performance Evaluation of Hexagonal Array Adaptive Beamforming Algorithm Based on Inverse QR-RLS for Active Sonar Application

Journal of Algorithms & Computational Technology, 2009
In shallow water areas, to enhance underwater targets detection performance improve computation efficiency of active sonar, a computationally efficient adaptive beamformer (spatial filter) based on inverse QR (IQR) and recursive least-squares (RLS) is ...
Q. Wang, X. Pan
doaj   +1 more source

Lightweight Model for Fish Recognition Based on YOLOV5-MobilenetV3 and Sonar Images

Guangdong nongye kexue, 2023
【Objective】Cage biometrics and statistics are one of the key reference factors for marine pasture farming management. Aiming at the interference of reverberation noise and complex background, this paper constructs fish detection data sets under different
Yizhi LUO, Huazhong LU, Xingxing ZHOU, Yu YUAN, Haijun QI, Bin LI, Zhichang LIU   +6 more
doaj   +1 more source

Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt, Eya Khadhraoui, Sebastian J. Müller, Katja Neumann, Hendrik Mattern, Sven G. Meuth, Valentina Perosa, Andreas Charidimou, Stefanie Schreiber   +8 more
wiley   +1 more source

An Improved Array Steering Vector Estimation Method and Its Application in Speech Enhancement

EURASIP Journal on Advances in Signal Processing, 2005
We propose a robust microphone array for speech enhancement and noise suppression. To overcome target signal cancellation problem of conventional beamformes caused by array imperfections or reverberation effects, the proposed method adopts arbitrary ...
Meng Hwa Er, Zhu Liang Yu
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Simulation Study on Detection and Localization of a Moving Target Under Reverberation in Deep Water

Journal of Marine Science and Engineering
Deep-water reverberation caused by multiple reflections from the seafloor and sea surface can affect the performance of active sonars. To detect a moving target under reverberation conditions, a reverberation suppression method using multipath Doppler ...
Jincong Dun, Shihong Zhou, Yubo Qi, Changpeng Liu   +3 more
doaj   +1 more source

Inverse Filtering and Principal Component Analysis Techniques for Speech Dereverberation

Advances in Electrical and Electronic Engineering, 2016
In this work, we present a single channel approach for early and late reverberation suppression. This approach can be decomposed into two stages. The first stage employs the inverse filter to augment the signal-to-reverberant energy ratio.
Mohamed Anouar Ben Messaoud, Aicha Bouzid   +1 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source