Results 181 to 190 of about 6,874 (266)

GPX4 Inhibitor Resistance and Metastatic Features in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study establishes breast cancer cell lines that are resistant to glutathione peroxidase 4 inhibitors (GPX4i) in vitro and investigates the metastatic capacity of the GPX4i‐resistant versus parental lines in vivo. GPX4i‐resistant cells survive upon intravenous injection, but lose capacity to spontaneously metastasize.
Marie Sabatier   +16 more
wiley   +1 more source

Nuclear Spin‐Free 70Ge/28Si70Ge Quantum Well Heterostructures Grown on Industrial SiGe‐Buffered Wafers

open access: yesAdvanced Science, EarlyView.
Hyperfine coupling to 29Si$^{29}{\rm Si}$ and 73Ge$^{73}{\rm Ge}$ nuclear spins limits hole spin‐qubit coherence in Ge heterostructures. We demonstrate device‐grade, nuclear‐spin‐free 70Ge$^{70}{\rm Ge}$/28Si70Ge$^{28}{\rm Si}^{70}{\rm Ge}$ quantum wells grown on industrial SiGe buffers with minimal use of enriched precursors.
Patrick Daoust   +11 more
wiley   +1 more source

Removal of syndesmotic screws - is sonography a precise and efficient method of guidance? [PDF]

open access: yesBMC Musculoskelet Disord
Eckstein C   +4 more
europepmc   +1 more source

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

open access: yesAdvanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong   +21 more
wiley   +1 more source

Ultrasound‐Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications

open access: yesAdvanced Science, EarlyView.
This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang   +5 more
wiley   +1 more source

Prompt Engineering Accelerates the Data‐Driven Discovery of Photocatalysts via an LLM‐Based Model Ensemble Strategy

open access: yesAdvanced Science, EarlyView.
This work establishes a pipeline that transforms fragmented literature into a structured database for graphitic carbon nitride photocatalyst discovery. A prompt‐engineered, cross‐model large language model ensemble automates high‐fidelity extraction, enabling interpretable machine learning to identify dominant performance descriptors. These data‐driven
Dianyuan Li   +7 more
wiley   +1 more source

Strong long-term variability in active galactic nuclei affects virial black hole mass measurements. [PDF]

open access: yesNat Commun
Amrutha N   +7 more
europepmc   +1 more source

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