Results 31 to 40 of about 167,467,598 (270)
, 2022 Thesis title: Burden of proof The subject of the diploma thesis is the institute of the burden of proof, with emphasis on the manifestations of individual constitutive components of the burden of proof, especially in civil contentious declaratory ...
Sudek, Matouš
core
The Reconstruction of the Reversal of the Burden of Proof Verificationin Corruption Delict [PDF]
International Journal of English Literature and Social Sciences, 2018 The reverse proof system adopted in the Act Number 31 of 1999 concerning the Eradication of Corruption as amended and supplemented by the Act Number 20 of 2001 Amendment to thye Act Number 31 of 1999 is a limited and balanced reverse verification system. This is contained in the general explanation of the Act.
openaire +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Partial Reversal Acyclicity [PDF]
, 2011 Partial Reversal (PR) is a link reversal algorithm which ensures that the underlying graph structure is destination-oriented and acyclic. These properties of PR make it useful in routing protocols and algorithms for solving leader election and mutual ...
Nancy Lynch +4 more
core +1 more source
Brazilian Neurosurgery, 2020 Introduction The neurosurgical practice often involves situations that require rapid and immediate decision making, and a very low margin for error may eventually lead to an unsatisfactory clinical outcome.
Leandro Pretto Flores +1 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Burden of Proof Reversal in Criminal Acts of Money Laundering
Mulawarman Law Review, 2019 This study aims to analyze the burden of proof reversal system in handling cases of money laundering. This type of research is normative juridical legal research. The results of this study indicate that in the reversal system of the burden of proof of criminal acts of money laundering, each party has a burden of proof, the public prosecutor is burdened
Muhammad Khusnul Fauzi Zainal +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source