Results 121 to 130 of about 1,204 (263)

Multidisciplinary Strategies for Targeting Tumor Dormancy in Breast Cancer Therapeutics: Hallmarks, Mechanism, and Approaches

iMetaMed, EarlyView.
Clinical phases and classification of breast tumor dormancy. Tumor dormancy is described as the period after treatment until residual tumor cells become detectable as relapsing disease in clinic. During the period of clinical tumor dormancy, tumor mass dormancy and cellular dormancy may coexist.
Shu Chen, Hui Chen, Vijaya Raghavan, Jing Huang, Jin Wang   +4 more
wiley   +1 more source

Opium trade and use during the Late Bronze Age: Organic residue analysis of ceramic vessels from the burials of Tel Yehud, Israel

Archaeometry, EarlyView., 2022
Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares, Eriola Jakoel, Ron Be’eri, Oded Lipschits, Ronny Neumann, Yuval Gadot   +5 more
wiley   +1 more source

Data-Driven Neural Network Model to Predict Equivalent Circulation Density ECD

, 2019
Equivalent circulation density (ECD) is vital in drilling operations. Poor management of ECD can lead to many drilling obstacles that can increase the delivery time of the well.
Rusul A. Mutar, Al-Bazzaz, Waleed H., Waleed H. Al-Bazzaz, Shari Dunn-Norman, Al-Alwani, Mustafa A., Dunn-Norman, Shari, Husam H. Alkinani, Abo Taleb Al-Hameedi, Mustafa A. Al-Alwani, Al-Hameedi, Abo Taleb T., Alkinani, Husam H., Mutar, Rusul A.   +11 more
core   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

The Relation Between Two Types of Frequent Wave Breaking Over Southeastern Siberia and Different Conditions of Unseasonable Midsummer Weather Over Japan

International Journal of Climatology, EarlyView.
To analyze the different morphologies of Rossby wave breaking over Eastern Siberia and their relationships with the anomalous patterns of temperature and precipitation that cause unseasonable midsummer weather conditions over Japan, we performed regression analyses against the interannual variabilities of the anticyclonic and cyclonic Rossby wave ...
Kazuto Takemura
wiley   +1 more source

Late Quaternary climatic variability in the Eastern Mediterranean recorded in Hermes Cave, Corinth Rift, Greece

Journal of Quaternary Science, EarlyView.
ABSTRACT The Greek peninsula lies at the intersection of major atmospheric circulation systems, making it a key location for reconstructing past climate variability in the Eastern Mediterranean. In this study, we present a new high‐resolution multi‐proxy speleothem record from Hermes Cave, located on the shoulder of the Corinth Rift in southern Greece.
Ch. Pennos, S. Pechlivanidou, S. Modestou, A. Persoiu, S.F.M. Breitenbach, U. Ninnemann, R.L. Gawthorpe, J. Maccali, S‐E. Lauritzen, R.Ø. Skoglund, Th. Thuesen   +10 more
wiley   +1 more source

Raman Line Scan Analyses and a New Hypothesis for the Formation of Anatase‐Hosting Microbialites: Study of the Stromatolites From Saint‐Jean‐de‐la‐Rivière, Cotentin, France

Journal of Raman Spectroscopy, EarlyView.
Micrometer analysis of millimeter lines of Raman spectra concludes in the association of anatase and graphitized organic matter (graphogen). The photosynthetic microorganisms at the origin of the microbialites produce O2, which is transformed by TiO2 into reactive species that, in turn, decompose the organic matter of the microorganisms. ABSTRACT Raman
Marie‐Paule Bassez
wiley   +1 more source

Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) is a life‐threatening stroke subtype that lacks effective drug therapy. In the context of ICH, neuroinflammation, and ferroptosis are key contributors to secondary brain injury. In this study, we assessed the neuroprotective effects of matrine (MAT) and its mechanism of action involving the HMGB1/RAGE axis in an ...
Pan‐Di Chen, Tao‐Tao Shi, Dan‐Yang Hu, Xiao‐Na Su, Jian‐Xiang Jin, Mao‐Song Chen, Hao Wang, Wei Chen   +7 more
wiley   +1 more source

The Bazaar as a Model for Knowledge Work

Knowledge and Process Management, EarlyView.
ABSTRACT This paper presents fieldwork that extends existing metaphors of knowledge work as a process shaped by hierarchical or market forces. A qualitative, ethnographic study of six knowledge‐intensive businesses in two countries identifies striking parallels with the Middle Eastern bazaar in contrast to Western impersonal markets and hierarchies. We
Reed Elliot Nelson, Andrew B. Hargadon, José Osvaldo De Sordi   +2 more
wiley   +1 more source

EFFECT OF PDC BIT DESIGN AND DRILLING FLUID ON RATE OF PENETRATION FOR MULTI-LAYER FORMATION [PDF]

, 2014
The project focuses on the optimization of Polycrystalline Diamond Compact (PDC) drill bit design features for improvement in rate of penetration (ROP) for multi-layer formation.
BINTI MOHD HABIB, NURFATIN ADIBAH
core