Results 41 to 50 of about 1,204 (263)

Study on Gas–Solid Particle Dynamics and Optimal Drilling Parameters in Reverse Circulation DTH Drilling Based on CFD and Machine Learning

Applied Sciences
The reverse circulation pneumatic down-the-hole (DTH) drilling system employs percussive drilling to achieve high efficiency and strong adaptability across diverse rock formations. However, its cutting removal efficiency remains suboptimal.
Kunkun Li, Jing Zhou, Peizhi Yu, Hao Wu, Tianhao Xu   +4 more
doaj   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

Downhole geophysical data acquisition during reverse circulation drilling for mining [PDF]

ASEG Extended Abstracts, 2019
Measurement While Drilling (MWD) and Logging While Drilling (LWD) tools acquire geophysical and operational data from directly behind the bit during drilling operations.
Timothy Hopper, Matthew Schubert, Grand Joldes, Brendan Moran, Paul Kalisch, Mark Crumby, Nick Buters, Kai-Uwe Ott, Kamil Rogozinski, Quentin Morgan, Tom Neville, Harish Shanmugam, Ralf Zaeper, Jonathan Lowe, Andrew Prince   +14 more
openaire   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Structure Design and Adaptability Analysis of Sand Return Diversion Pipeline for Reverse Circulation Drilling

Shiyou jixie, 2020
To address the problem that conventional sand return pipeline cannot meet the sand return requirements of reverse circulation drilling technology, two new sand return pipeline schemes—U-shaped pipeline and catenary pipeline are proposed based on the ...
Kang Bo, Fan Honghai, Deng Song, Zhu Shuo, Shao Shuai, Ni Xingya, Liu Yali   +6 more
doaj  

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Orthogonal experimental research on the structural parameters of a novel drill bit used for ice core drilling with air reverse circulation

Journal of Glaciology, 2019
A new type of ice core drill bit, designed with a vane swirler, was developed for ice core drilling with air reverse circulation. An orthogonal experimental design method was employed to investigate the effects of the swirler structure parameters on the ...
Pinlu Cao, Qi Zhao, Zhuo Chen, Hongyu Cao, Baoyi Chen   +4 more
doaj   +1 more source

Research on technology and equipment system of large diameter shaft drilling based on gravity slagging

Meitan kexue jishu, 2023
The shaft is a key project, including the mining of shaft engineering minerals and the development and utilization of underground space. As the lower part of the proposed shaft has the advantage of a production system, the use of gravity slag removal is ...
LIU Zhiqiang, SONG Zhaoyang, CHENG Shouye, JING Guoye, ZHAO Junxian, CHEN Yun, ZHAO Like   +6 more
doaj   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Modeling of drilling water supply wells with airlift reverse flush agent circulation

Naukovyi Visnyk Natsionalnoho Hirnychoho Universytetu, 2023
Purpose. Determination of the influence of mining and geological conditions of drilling hydrogeological wells with backwash on the technological parameters of the airlift method of cleaning it from drilled rock and the properties of the ascending flow of aerated washing liquids. Methodology.
M. T Biletskiy, B. T Ratov, A. K Sudakov, D. А Sudakova, B. R Borash   +4 more
openaire   +1 more source