Results 91 to 100 of about 3,284,407 (297)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Officer-Involved Domestic Violence: The Mediating Factors [PDF]

, 2018
Domestic and family violence has been a critical issue in contemporary society. Efforts have been made in researching the causes, effects, and mediating factors of domestic violence in relation to the workplace.
Baron, Isaac
core   +1 more source

Comparison of the atomic level structure of the plastic crystalline and the liquid phases of CBr2Cl2: neutron diffraction and Reverse Monte Carlo modeling

, 2013
Neutron diffraction results obtained for plastic crystalline dichlorodibromomethane (CBr2Cl2) have been modelled by means of the Reverse Monte Carlo method.
Cuello, Gabriel Julio, Pardo, Luis Carlos, Pothoczki, Szilvia, Rovira-Esteva, Muriel, Tamarit, Josep Lluis, Temleitner, László   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

From experience to expectation: The reverse effect of power on purchasing impulsiveness. [PDF]

Front Psychol, 2023
Wang Y, Yao T, Qiu Q.
europepmc   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Test system creation for analysis of template switching effect during a reverse transcription in vitro

Тонкие химические технологии, 2011
We investigated an in vitro system for the analysis of template switching effect of RNA-dependent DNA-polymerase during reverse transcription reaction. An RT-PCR-based approach was realized. An RNA sample was used as a template. The RNA contains a region
A. Y. Komkov, Y. B. Lebedev, V. I. Shvets   +2 more
doaj  

Concentration Polarization in Reverse Osmosis Membranes: Effect of Membrane Splitting

Chemical Engineering Transactions, 2014
We propose a simulation study in order to evaluate the effects of concentration polarization damping by splitting a single spiral-wound membrane module in two units connected in series inside the same shell.
A.P. Reverberi, B. Fabiano, C. Cerrato, V.G. Dovì   +3 more
doaj   +1 more source

Reverse effect of Semaphorin-3F on rituximab resistance in diffuse large B-cell lymphoma via the Hippo pathway. [PDF]

Chin Med J (Engl), 2023
Li Q, Ma N, Li X, Yang C, Zhang W, Xiong J, Zhu L, Li J, Wen Q, Gao L, Yang C, Rao L, Gao L, Zhang X, Rao J.   +14 more
europepmc   +1 more source