Results 241 to 250 of about 3,284,407 (297)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Understanding the role of hypertension in stroke outcomes using Bayesian analysis. [PDF]

Sci Rep
Akhmedullin R, Zhakhina G, Issanov A, Aimyshev T, Sarria-Santamera A, Crape B, Salustri A, Arupzhanov I, Beyembetova A, Ablayeva A, Biniyazova A, Seyil T, Abdukhakimova D, Gaipov A.   +13 more
europepmc   +1 more source

Reverse Buffering Effects of Active Coping on Suicidal Ideation in Bullied Adolescents: Age Cohort Differences. [PDF]

Behav Sci (Basel)
Liu S, Xiong Q, Gao Y, Wang L, Yu Q.
europepmc   +1 more source

Glutamine and allergic rhinitis: A bidirectional two-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Fan S, Guan Z, Ding Y, Chen W, Su S, Bai H, Li L.   +6 more
europepmc   +1 more source

Gallbladder disease and colorectal cancer: a two-sample bidirectional Mendelian randomization study. [PDF]

Discov Oncol
Hu Q, Sun J.
europepmc   +1 more source

Degenerated meniscus alters knee osteoarthritis-related gene expression in articular chondrocytes through paracrine mechanisms. [PDF]

Sci Rep
Guo B, Kanamoto T, Aihara M, Yamakawa S, Yokoyama T, Ebina K, Tanaka H, Nakata K.   +7 more
europepmc   +1 more source

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Reverse Macklin effect

Indian Journal of Thoracic and Cardiovascular Surgery, 2022
The Macklin effect is associated with alveolar rupture causing a centripetal spread of air along the peribronchovascular interstitial sheath leading to pneumomediastinum, usually seen in ventilator-related barotrauma or blunt chest trauma. We are presenting a peculiar case of iatrogenic (post-intubational) tracheal injury with massive subcutaneous ...
Rohan Reddy Chinthareddy, Karthik Ashok, Srirangapatna Varadaraj Srikrishna, Vijay Cholenahalli Lingaraju   +3 more
openaire   +2 more sources