Results 241 to 250 of about 4,446,471 (346)

Reverse-engineering method for XPCS studies of non-equilibrium dynamics. [PDF]

IUCrJ, 2022
Ragulskaya A, Starostin V, Begam N, Girelli A, Rahmann H, Reiser M, Westermeier F, Sprung M, Zhang F, Gutt C, Schreiber F.   +10 more
europepmc   +1 more source

Information mining and mechanical analysis of new-generation aero-engine turbine discs with industrial computed laminography reverse engineering

Yenan Gao
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Reverse engineering of feedforward cortical-Hippocampal microcircuits for modelling neural network function and dysfunction. [PDF]

Sci Rep
Hanssen KS, Winter-Hjelm N, Niethammer SN, Kobro-Flatmoen A, Witter MP, Sandvig A, Sandvig I.   +6 more
europepmc   +1 more source

Reverse engineering for reconstructing baseline features of dry age-related macular degeneration in optical coherence tomography. [PDF]

Sci Rep, 2022
Wang S, Wang Z, Vejalla S, Ganegoda A, Nittala MG, Sadda SR, Hu ZJ.   +6 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Supercomputer framework for reverse engineering firing patterns of neuron populations to identify their synaptic inputs. [PDF]

Elife
Chardon MK, Wang YC, Garcia M, Besler E, Beauchamp JA, D'Mello M, Powers RK, Heckman CJ.   +7 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Bridging human and machine intelligence: Reverse-engineering radiologist intentions for clinical trust and adoption. [PDF]

Comput Struct Biotechnol J
Awasthi A, Le N, Deng Z, Agrawal R, Wu CC, Van Nguyen H.   +5 more
europepmc   +1 more source