Results 171 to 180 of about 574,351 (267)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Patient Expectations and Dentists' Perceptions of Those Expectations in Dental Implant Therapy: A Mirror-Design Study. [PDF]

Healthcare (Basel)
Özdemir A, Sevimay MA, Karakaş E.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Preliminary validation of the health and social care professionals' knowledge and attitudes towards later-life intimacy and sexuality (HSCP-KALLIS) scale. [PDF]

BMC Geriatr
Chen YH, Bannatyne A, Jones C, Horne M, Asil M.   +4 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Development and psychometric validation of SADAR-PrEP, an Indonesian PrEP knowledge and attitudes instrument. [PDF]

Sci Rep
Arifin B, Vinegia A, Usmar U, Alkaff SD, Febriana SA, Alfieri A, Rauf S, Zulkarnain Z, Perwitasari DA, Purba FD, Ardiansyah A, Alkaff FF, Salamah S, Kristina SA, Sarifah LM, Amin IH, Pribadi FW, Wertheimer A, Postma MJ, Syahrir M, Rokhman MR.   +20 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Development and Initial Psychometric Evaluation of the Adolescent Oral and Maxillofacial Health Knowledge-Attitude-Practice and Self-Efficacy Questionnaire (AOMH-KAPQ). [PDF]

Healthcare (Basel)
Zhang L, Liu X, Cui L, Yang X, Hou X, Hou L.   +5 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Measuring attitudes toward artificial intelligence: validation of the Chinese ATTARI-12 and invariance across genders and academic disciplines. [PDF]

Front Psychol
Li P, Chong YY, Man W, Li H.
europepmc   +1 more source