Results 51 to 60 of about 574,351 (267)
Frontiers in MicrobiomesOil reservoirs represent extreme environments where anaerobic degradation profoundly influences oil composition and quality. Despite the common observation of biodegraded oil, the microbial degradation rates remain largely unknown.
Sebastian Beilig +3 more
doaj +1 more source
Human factors in hardware reverse engineering
, 2022 Das Reverse-Engineering von Mikrochips ist ein komplexer Prozess, der deren Integrität bedroht. Dabei hängt der Erfolg von den Fähigkeiten der Analysten ab. Diese Dissertation hat das Ziel, die Vorgehensweisen und kognitiven Prozesse von Menschen beim Hardware-Reverse-Engineering zu analysieren, um daraus neuartige Gegenmaßnahmen abzuleiten.
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The Possibility of Psychical Factors in Illusions of Reversed Motion [PDF]
Science, 1906 n ...
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
A Multidimensional Assessment of the Impact of Healthcare Volunteering in a War-Affected Setting
European Journal of Investigation in Health, Psychology and EducationBackground: Medical students who volunteer during armed conflict may help sustain overwhelmed health services while experiencing concurrent social, academic, psychological, and physical consequences.
Latefa Ali Dardas +4 more
doaj +1 more source
Celiprolol and Risk Factor Reversal in Hypertension
Journal of Cardiovascular Pharmacology, 1989 beta-Blockers reduce hypertension effectively and safely. However, their overall efficacy is a balance between their influence on blood pressure and their influence on other important risk factors. Thus, whereas a drug may ameliorate the primary blood pressure marker of the syndrome, this effect may be negated by enhancement of aggressive cofactors ...
openaire +3 more sources