Results 281 to 290 of about 2,173,029 (360)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Plasmid-Based Reverse Genetics System Enabling One-Step Generation of Genotype 3 Hepatitis E Virus. [PDF]

Viruses
Kobayashi T, Nishiyama T, Yamada K, Murata K, Okamoto H.   +4 more
europepmc   +1 more source

Interactome and reverse genetics studies of regulatory subunits of Plasmodium falciparum casein kinase [PDF]

, 2010
Guillem Dayer
openalex  

Development of ENTV reverse genetics system and phenotypic evaluation of rescued virus reveals host-specific replication patterns in mosquitoes [PDF]

Marina Fujii, Emily N. Gallichotte, Irma Sánchez-Vargas, Brooke M. Enney, Lauren E. Malsick, Gregory D. Ebel, Brian J. Geiss   +6 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Establishment of a reverse genetics system for an epidemic strain of porcine rotavirus JXAY01 type G5P[23]I12. [PDF]

Front Vet Sci
Liu C, Wei H, Zhang X, Wu W, Shen Z, Luo F, Deng S.   +6 more
europepmc   +1 more source

Forward and reverse genetics approaches to uncover metabolic aging pathways in Caenorhabditis elegans

, 2017
Arwen W. Gao, Jelmi uit de Bos, Mark G. Sterken, Jan E. Kammenga, Reuben L. Smith, Riekelt H. Houtkooper   +5 more
openalex   +1 more source

Reverse genetics system

An nCoV full-length cDNA clone is available and this has been used to recover infectious nCoV from (RNA-) transfected mammalian cells.
openaire   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Design and construction of a fast synthetic modified vaccinia virus Ankara reverse genetics system for advancing vaccine development. [PDF]

Front Microbiol
Gao Z, Wang B, Liu T, Zhao Z, Xu J, Zhao X, Zhang Z, Jia Z, Yang Y, Wu S, Chen W, Hou L.   +11 more
europepmc   +1 more source