Results 101 to 110 of about 4,479,330 (277)

VISUALIZATION OF THE REVERSED MOTION WHEN SOLVING PROBLEMS IN MECHANICS BY GRAPHICAL METHODS

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2016
The article considers the possibility to visualize the process of solving graphic problems of mechanics of mechanisms in dynamic mode by creating a mini-film, which can be used by a teacher in lectures or in practical classes, and by students for self-studying the course "The- ory of mechanisms and machines"
V M Matveev, V A Romanova, S V Strashnov
openaire   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Electrostatic Latch Mechanism for Handling Projection on Arrayed Vertical Motion System [PDF]

open access: yes, 2007
We have previously proposed an arrayed vertical motion system based on a tulip-shaped electrostatic clutch for producing haptic displays. The system has an advantage in that it is able to individually operate arrayed end-effecter elements with high-power
Sasaki, H.   +7 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

曲柄滑块-非圆齿轮组合机构中节曲线反求设计

open access: yesJixie chuandong, 2014
The slider-crank-non-circular gear combinations mechanism is studied,for obtaining the ideal slider velocity curve,the non-circular gear pitch curve design is divided into two sections of constant stroke and transition stroke.Based on the SolidWorks ...
许茏
doaj  

Structure Design and Static Analysis of the Underactuated Three-knuckle Manipulator with a Reverse Rope-pulley Mechanism

open access: yesJixie chuandong, 2023
Based on the characteristics of the link structure and the rope pulley structure, a new reverse rope-pulley mechanism is proposed. The principle and motion characteristics of the new mechanism are introduced, and the structure of a three-knuckle ...
Piao Jinsheng   +4 more
doaj  

Auditory motion capturing ambiguous visual motion [PDF]

open access: yes, 2012
In this study, it is demonstrated that moving sounds have an effect on the direction in which one sees visual stimuli move. During the main experiment sounds were presented consecutively at four speaker locations inducing left or rightward auditory ...
Elena Galeano   +23 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Velocity analysis of planar mechanisms based on conversion mechanism

open access: yesJixie chuandong
ObjectiveIn the scenario where the dimensions of the mechanism and the motion law of the driving link are already known, the purpose of kinematic analysis of mechanisms is to determine the motion characteristics of other links within the mechanism and to
LI Xiuming, WANG Changlu, DONG Zhifeng
doaj  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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