Results 141 to 150 of about 7,015,876 (218)

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Multifunctional Hybrid Nanomedicines for Neurodegenerative Diseases: A Paradigm Shift from Rational Design to Clinical Translation. [PDF]

Int J Nanomedicine
Wu Y, Wang M, Li T, Huang Z, Wu M, Sun T, Cong H.   +6 more
europepmc   +1 more source

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

Advanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu, Qishuai Chen, Yan Ma, Yang Liu, Xianing Dong, Wenjuan Wei, Jianxin Du, Shusheng Qiu, Maojin Tian, Peiqing Zhao   +9 more
wiley   +1 more source

Site-Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids. [PDF]

Angew Chem Int Ed Engl
Sarkar R, Joshi M, Chatterjee A.
europepmc   +1 more source

Receptogenesis in a Vascularized Robotic Embodiment

Advanced Science, EarlyView.
Functional augmentation of situated robots via ex novo hardware generation extends physical adaptability. Drawing inspiration from open circulatory systems for mass and function redistribution, this study presents a vascularized robotic composite exhibiting receptogenesis ‐ the on‐demand construction of sensors ‐ from internal fluid reserves based on ...
Kadri‐Ann Pankratov, Leonid Zinatullin, Hans Priks, Adele Metsniit, Urmas Johanson, Tarmo Tamm, Alvo Aabloo, Edoardo Sinibaldi, Indrek Must   +8 more
wiley   +1 more source

Engineering controllable CAR T-cell therapies: from binary safety switches to programmable immunity. [PDF]

Front Immunol
Smirnov S, Zaritskey Y, Salogub G, Fonin A.   +3 more
europepmc   +1 more source

Molecular‐Level Pore Engineering for Precise Separation via Active Solvent‐Mediated Interfacial Polymerization

Advanced Science, EarlyView.
We demonstrate that microemulsion solvents can actively template molecular‐level pores within selective layer during interfacial polymerization. By creating localized quasi‐homogeneous polymerization zones, the membrane achieved a 7.1‐fold enhancement in water permeance with increased selectivity.
Feng Li, R. M. G. Rajapakse, Yuxin Mou, Deyin Hou, Min Yang   +4 more
wiley   +1 more source

Programmable robotic textile with closed-loop self-sensing and active actuation. [PDF]

Sci Adv
Liu H, Tang L, Zhang C, Zhou R, Ma J, Zhao Y, Zhang J, Dong G, Chen H, Li W, Hu H, Ma X, He Q.   +12 more
europepmc   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Multi-Stimuli Responsive Viologen-Crosslinked Eutectogels Derived From Natural Deep Eutectic Solvents for Information Security and Motion Detection. [PDF]

Adv Sci (Weinh)
Bai Z, Koay WL, Oh XY, Truong VX.
europepmc   +1 more source