Results 21 to 30 of about 94,375 (298)
Patterns of deposition from experimental turbidity currents with reversing buoyancy [PDF]
, 2010 Turbidity currents are turbulent, sediment-laden gravity currents which can be generated in relatively shallow shelf settings and travel downslope before spreading out across deep-water abyssal plains.
Pritchard, David +2 more
core +1 more source
PARP1 Might Substitute HSF1 to Reactivate Latent HIV-1 by Binding to Heat Shock Element
Cells, 2022 At present, the barrier to HIV-1 functional cure is the persistence of HIV-1 reservoirs. The “shock (reversing latency) and kill (antiretroviral therapy)” strategy sheds light on reducing or eliminating the latent reservoir of HIV-1. However, the current
Xinfeng Xu +10 more
doaj +1 more source
Cell Death Discovery, 2023 Therapy resistance remains a huge challenge for current breast cancer treatments. Exploring molecular mechanisms of therapy resistance might provide therapeutic targets for patients with advanced breast cancer and improve their prognosis.
Yinghuan Cen +6 more
doaj +1 more source
Lnc(ing)RNAs to the “shock and kill” strategy for HIV-1 cure
Molecular Therapy: Nucleic Acids, 2021 The advent of antiretroviral therapy almost 25 years ago has transformed HIV-1 infection into a manageable chronic condition, albeit still incurable. The inability of the treatment regimen to eliminate latently infected cells that harbor the virus in an ...
Saikat Boliar, David G. Russell
doaj +1 more source
Current reversals in a rocking ratchet: The frequency domain [PDF]
Physical Review E, 2011 Motivated by recent work [D. Cubero et al., Phys. Rev. E 82, 041116 (2010)], we examine the mechanisms which determine current reversals in rocking ratchets as observed by varying the frequency of the drive. We found that a class of these current reversals in the frequency domain are precisely determined by dissipation-induced symmetry breaking.
Wickenbrock, Arne +4 more
openaire +5 more sources
Efficient Magnetization Reversal with Noisy Currents
Physical Review Letters, 2006 We propose to accelerate reversal of the ferromagnetic order parameter in spin valves by electronic noise. By solving the stochastic equations of motion we show that the current-induced magnetization switching time is drastically reduced by a modest level of externally generated current (voltage) noise.
Wetzels, W. (author) +2 more
openaire +5 more sources
Frontiers in Microbiology, 2020 One of the most explored therapeutic approaches aimed at eradicating HIV-1 reservoirs is the “shock and kill” strategy which is based on HIV-1 reactivation in latently-infected cells (“shock” phase) while maintaining antiretroviral therapy (ART) in order
Amina Ait-Ammar +9 more
doaj +1 more source
Non-Traditional Systemic Treatments for Diabetic Retinopathy: An Evidence-Based Review [PDF]
, 2015 The rapid escalation in the global prevalence diabetes, with more than 30% being afflicted with diabetic retinopathy (DR), means it is likely that associated vision-threatening conditions will also rise substantially.
Simó, R +15 more
core +1 more source
Cancer Medicine, 2020 We aimed to explore the molecular substrate underlying EGFR‐TKI resistance and investigate the effects of N‐acetylcysteine (NAC) on reversing EGFR‐TKI resistance.
Jun Li +5 more
doaj +1 more source