Results 131 to 140 of about 7,281,976 (241)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Motivations and barriers to engaging in peer review: a qualitative study. [PDF]
Res Integr Peer RevFernandes JB +4 more
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Book Review: Principles of Health Interoperability HL7 and SNOMED [PDF]
Healthcare Informatics Research, 2014 Young-Taek Park
doaj +1 more source
Mapping the Clinical Evidence on Remimazolam in Anaesthesia: A Protocol for a Scoping Review. [PDF]
Acta Anaesthesiol ScandNilsson EHVS, Abood I, Møller AM.
europepmc +1 more source