Results 221 to 230 of about 19,156,821 (237)

Reply to: Accurately synthesising evidence for long COVID rehabilitation. [PDF]

ERJ Open Res
Chakraverty S, Maru N, Megaritis D, Hume E, Chynkiamis N, Cucato G, Wilhelm EN, Vogiatzis I.   +7 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Conceptualizations of compassion in the context of dementia caregiving: A scoping review protocol. [PDF]

PLoS One
Kokorelias KM, Simpson R, Beleno R, Cameron J, Dove E, Kuluski K, McAiney C, Munce SEP, Quinn K, Saragosa M, Wasilewski M, Yous ML, Zhu L, Wu J, Stall N.   +14 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Family Outcomes Associated With Occupational Trauma Exposure in Frontline Workers: Protocol for a Scoping Review. [PDF]

JMIR Res Protoc
Cogan N, Ross M, Miller R, Johnson T, Iqbal Z, Kirk A, Hodgson W, Whittaker S, Siddaway A, Skovgaard A, Graham P.   +10 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Patient and Public Involvement and Engagement in Pediatric Health Research: A Systematic Review. [PDF]

Health Expect
Stadler V, Mozun R, Strohm J, Consortium S, Caruso C, Posfay-Barbe KM, Hagmann C.   +6 more
europepmc   +1 more source

Cultural adaptation and psychometric properties of health-related quality of life tools used in persons living with diabetes mellitus studies conducted in Ethiopia: a protocol for a scoping review. [PDF]

BMJ Open
Awoke W, Alene GD, Admasie A, Tarekegn G, Yitayal M, Getahun FA.   +5 more
europepmc   +1 more source