Results 121 to 130 of about 21,282,199 (350)

Vision toolkit part 1. Neurophysiological foundations and experimental paradigms in eye-tracking research: a review

Frontiers in Physiology
Eye-tracking research offers valuable insights into human gaze behavior by examining the neurophysiological mechanisms that govern eye movements and their dynamic interactions with external stimuli.
Quentin Laborde, Quentin Laborde, Axel Roques, Axel Roques, Matthieu P. Robert, Matthieu P. Robert, Allan Armougum, Nicolas Vayatis, Ioannis Bargiotas, Laurent Oudre, Pierre-Paul Vidal, Pierre-Paul Vidal   +11 more
doaj   +1 more source

Evaluation of confirmatory data following the Article 12 MRL review for pyraclostrobin [PDF]

, 2018
Alba Brancato, Daniela Brocca, Luis Carrasco Cabrera, Chloé De Lentdecker, Zoltán Erdős, Lucien Ferreira, Luna Greco, Samira Jarrah, Dimitra Kardassi, Renata Leuschner, Alfonso Lostia, Christopher Lythgo, Paula Medina, Ileana Miron, Tünde Molnar, Ragnor Pedersen, Hermine Reich, Angela Sacchi, Miguel Santos, Alois Stanek, Juergen Sturma, José Tarazona, Anne Theobald, Bénédicte Vagenende, Laura Villamar‐Bouza, Laura Villamar‐Bouza   +25 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Kan transkutan elektrisk nervestimulering lindre nevropatisk smerte?

Fysioterapeuten, 2006
In this article we have reviewed the research literature to find out if Transcutaneous Electrical Nerve Stimulation, known as TENS, can reduce pain and improve function for patients suffering from neuropathic pain. A literature search was made in medical
Anne Sofie Lofthus, Sara Maria Allen
doaj  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Influence of Selenium on Oxidative Stress in Athletes. Review Article. [PDF]

, 2016
Natalia Kois, Paulina Ler, Klaudia Piechanowska, Krzysztof Sieja, Michalina Stolarska, Joanna von Mach-Szczypińska   +5 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Role of Vascular Ultrasonography in COVID-19-- Review Article

, 2021
Nazeeha Waseem, Beenish Abbas, Usman Nazir, Hafsa Waseem, Abid Ali, Taiba Zulfiqar   +5 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source