Results 151 to 160 of about 87,137,076 (257)

Nanomaterial-based vaccines: An advanced approach against rotavirus: A review article. [PDF]

Hum Vaccin Immunother
Soroush Fard A, Kalantar K, Teimoori A, Barati M, Arezumand R, Fani M.   +5 more
europepmc   +1 more source

Review Article

, 1964
review ...
Daniells, Roy
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Review Article: Biomarkers in Liver Transplantation for Hepatocellular Carcinoma: Towards Precision Medicine. [PDF]

Aliment Pharmacol Ther
Ma Y, Li H, Chen H, Xu J, Ye Z, Li Y, Wu X, Chen J, Cao C, Zhang P, Zhao R, Li J, Zhu C, Zhuo J, Xu S, Xu X, Lu D.   +16 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Review Article: Implementation Challenges in Helicobacter pylori Management: Bridging Evidence and Real-World Practice. [PDF]

Aliment Pharmacol Ther
Quach DT, Liou JM, Gisbert JP, Leung WK, Moss SF, Fallone CA, Katelaris P, Schulz C, Kayamba V, Zhou L, Vu NTH, Vilaichone RK, Miftahussurur M, Setshedi M, Riquelme A, Yadegar A, Lee YY, Ishibashi F, Jung HY, Coelho LG, Suzuki H, Lee YC, Megraud F, Mahachai V, Sugano K, Malfertheiner P.   +25 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

The Role of Platelets in Pulmonary Hypertension: From Activation to Pulmonary Vascular Remodeling-A Review Article. [PDF]

Biomedicines
Wszelaki P, Karczmarska A, Szymoniuk S, Grześk G, Włodarczyk Z, Sikora J.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Nasal kaposiform hemangioendothelioma: a rare disease in a rare location-a review article with a case report. [PDF]

Front Surg
Alkholaiwi F, Yun Choi J.
europepmc   +1 more source