Results 141 to 150 of about 355,832 (313)
Effect of terahertz irradiation on DNA damage repair in living cells
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Unleashing Competition in EU Business Services. CEPS Policy Brief No. 284, 24 September 2012 [PDF]
In most EU member states, the business services industry has booked no productivity growth during the last two decades. The industry’s performance in the other member states was weaker than that of its US counterparts.
Kox, Henk
core
The Adoption of Remedies under Regulation 1/2003: between Success and Coherence
Rita Vasconcelos
doaj +1 more source
From competitiveness of enterprises to competitiveness of cities – a theoretical review
Purpose: The aim of this paper is to present international studies concerning competitiveness, focusing on competitiveness of cities. Design/methodology/approach: First a review of literature is provided referring to multifaceted definitions of competitiveness. Next selected approaches to city competitiveness are presented.
openaire +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
Regulatory Writing Competition Winners
Healthy school lunches, complex financial regulation, and pizza purveyors; in this series, The Regulatory Review features essays discussing regulation on each of these topics. The essays, written by student authors from the University of Pennsylvania Law
The Regulatory Review
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