Results 31 to 40 of about 15,080,823 (252)

The Role of Innovation in the Analysis of Abuse of Dominance in Digital Markets: The Analysis of Chosen Practices of Google Search

Market and Competition Law Review, 2019
Competition investigations in digital markets focus increasingly on future markets, and incentives to invest and innovate play here a larger role than in traditional "brick and mortar" industries.
Beata Mäihäniemi
doaj   +1 more source

The value of liability tests in abuses of dominance

Market and Competition Law Review, 2023
Currently, there is a debate in the European Union regarding the European Commission’s approach in assessing the behaviour of dominant firms. It is argued that as digital ecosystems become more powerful, there is increasing pressure on the Commission to
Mariateresa Maggiolino
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Competition Narrative for Modern Business Professionals

Современная конкуренция
He presented review of the new edition of the textbook “Competition in Entrepreneurship” indicates that the author highlights the process of participation in competition as the main subject of study.
Yuriy I. Korobov
doaj   +1 more source

Humpty Dumpty and High-Risk AI Systems: The Ratione Materiae Dimension of the Proposal for an EU Artificial Intelligence Act

Market and Competition Law Review, 2022
On 21 April 2021, the European Commission proposed a Regulation laying down harmonised rules on artificial intelligence (hereafter, “AI”). This so-called Artificial Intelligence Act (hereafter, the “Proposal”) is based on European values and fundamental
Jérôme De Cooman
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Manipulation into unsustainable consumer choices as exploitative abuse of dominance

Market and Competition Law Review
This article oscillates around the intersection of sustainability and digital platforms, which is an increasingly important and complex area of study in which digital platforms can have both a positive and a negative influence.
Beata Mäihäniemi
doaj   +1 more source