Results 191 to 200 of about 222,993 (250)
Response to the letter to the editor regarding "Bio-3D printing of scaffold-free ADSC-derived cartilage constructs comparable to natural cartilage in vitro". [PDF]
Nonaka T +6 more
europepmc +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
From ChatGPT to DeepSeek: assessing the accuracy and readability of AI-generated erectile dysfunction responses. [PDF]
Demirhan K +4 more
europepmc +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
From setting to vetting: using artificial intelligence for Single Best Answer questions review. [PDF]
Ng O, Han SP, Lee MHM, Phua DH.
europepmc +1 more source

