Results 131 to 140 of about 2,102,678 (308)

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Response to “Letter to the editor: Labral calcification plays a key role in hip pain and symptoms in femoroacetabular impingement”

Journal of Orthopaedic Surgery and Research, 2020
Giovanni Trisolino, Marta Favero, Dante Dallari, Enrico Tassinari, Francesco Traina, Miguel Otero, Steven R. Goldring, Mary B. Goldring, Chiara Carubbi, Roberta Ramonda, Stefano Stilli, Brunella Grigolo, Eleonora Olivotto   +12 more
doaj   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Where do we stand with revision surgery for recurrent carpal tunnel syndrome? A systematic review

JPRAS Open
Introduction: Recurrent carpal tunnel syndrome (CTS) after carpal tunnel release may require revision surgery, but the relative value of decompression, neurolysis, vascularised coverage, nerve wrapping, fat grafting, and other adjuncts remains uncertain.
Cheuk Ying Kyleen Kiew, Rachel Jia En Lai, David Kwan Ryung Lee, Dave Osinachukwu Duru, Wee Leon Lam   +4 more
doaj   +1 more source

The vascularised fibular graft for limb salvage after bone tumour surgery A MULTICENTRE STUDY

, 2015
Vascularised fibular grafts (VFGs) are a valuable surgical technique in limb salvage after resection of a tumour. The primary objective of this multicentre study was to assess the risk factors for failure and complications for using a VFG after resection
Hilven, P.H., Gibbons, M., Dijkstra, P.D.S., Cosker, T., van de Sande, M. A. J., van Drunen, G. K., Strackee, S.D., Sande, M.A.J. van de, Vooren, J. van, Giele, H., Bramer, J. A. M., Schaap, G. R., van Vooren, J., Jutte, P. C., Hilven, P. H., Strackee, S. D., Bayliss, L., Lahoda, L.U., Dijkstra, P. D. S., Schaap, G.R., Drunen, G.K. van, Jutte, P.C., Bramer, J.A.M., Lahoda, L. U.   +23 more
core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Facial nerve schwannoma in revision stapedotomy surgery

, 2004
We describe a male patient who presented a progressive conductive unilateral hearing loss 20 years after otosclerosis surgery. Computed tomography (CT) scan and magnetic resonance imaging (MRI) findings suggested a facial schwannoma in its tympanic ...
J. P., Lavieille, Schmerber, S.
core   +1 more source

Replacement and Revision Hip and Knee Surgery Projections up to the Year 2060: An Analysis Based on Data from the Romanian Arthroplasty Register

Medicina
Background and Objectives: Hip and knee replacement joint surgeries are experiencing constant growth, and anticipating future needs allows decision-makers and stakeholders involved in the healthcare system to allocate the necessary resources for safe and
Flaviu Moldovan, Liviu Moldovan
doaj   +1 more source

Recommendations for amendments to the Ohio constitution

, 1971
At head of title: State of Ohio.; Errata slip inserted in pt. 2.; Includes bibliographical references.; Harvested from the web on 7/9/12Part 1. Administration, organization, and procedures of the General Assembly -- pt. 2. State debt -- pt.
Ohio. Constitutional Revision Commission.
core  

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source