CSF Mitochondrial DNA: Biomarker of Body Composition and Energy Metabolism in Parkinson's Disease
ABSTRACT Objective Cerebrospinal fluid (CSF) cell‐free mitochondrial DNA (cf‐mtDNA) is a potential biomarker for Parkinson's disease (PD), but its clinical relevance remains unclear. We investigated associations between CSF cf‐mtDNA levels, body composition, nutritional status, and metabolic biomarkers in PD. Methods CSF cf‐mtDNA levels, defined as the
Yasuaki Mizutani +11 more
wiley +1 more source
Scedosporium Boydii disseminated infection complicating severe SARS-CoV-2 infection in an immunocompetent patient: a case report. [PDF]
Tenorio AMT, Roldán DM, Botero AIH.
europepmc +1 more source
Translation, cross-cultural adaptation and content validation of the Global Trigger Tool surgical module. [PDF]
Alpendre FT +4 more
europepmc +1 more source
Nerve Excitability in Asymptomatic Carriers and Amyotrophic Lateral Sclerosis Patients With C9orf72
ABSTRACT Objective We investigated the effects of C9orf72 mutation carriership on peripheral nerve excitability in asymptomatic individuals from families with a history of C9orf72 amyotrophic lateral sclerosis (ALS) and patients. Methods We included 47 asymptomatic individuals from families with a history of C9orf72 ALS, of whom 23 were carriers (C9 ...
Diederik J. L. Stikvoort García +3 more
wiley +1 more source
[Rapid review: effectiveness of the Wolbachia strategy for arbovirus controlRevisión sistemática rápida: efectividad de la estrategia de control con Wolbachia en la lucha contra las arbovirosis]. [PDF]
Angotti AA +3 more
europepmc +1 more source
ABSTRACT Objective Paroxysmal kinesigenic dyskinesia (PKD) is the most common hereditary paroxysmal movement disorder. The PRRT2 gene is the first identified causative gene and accounts for the majority of PKD. In this study, we investigated the pathogenicity of PRRT2 variants in the splice regions. Methods Patients with clinically suspected PKD and no
Jiao‐Jiao Xu +5 more
wiley +1 more source
Integrative and complementary healthcare practices for hypertension: a summary of recommended clinical guidelines. [PDF]
Silva MT +3 more
europepmc +1 more source
ABSTRACT Background Plasma p‐tau181 has proven to be a promising diagnostic and prognostic tool in the earliest phases of Alzheimer's disease (AD). We aimed to evaluate the prognostic role of p‐tau181 in predicting conversion to AD dementia and worsening in cognition in mild cognitive impairment (MCI) and subjective cognitive decline (SCD).
Giulia Giacomucci +12 more
wiley +1 more source
Revising the Subsystem Nurse’s A-Phase-Silicocarnotite within the System Ca3(PO4)2–Ca2SiO4 [PDF]
Patricia Ros-Tárraga +3 more
openalex +1 more source

