Results 41 to 50 of about 632,994 (309)

Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup

open access: yesAlzheimer's & Dementia
The National Institute on Aging and the Alzheimer's Association convened three separate work groups in 2011 and single work groups in 2012 and 2018 to create recommendations for the diagnosis and characterization of Alzheimer's disease (AD).
Clifford R Jack   +19 more
semanticscholar   +1 more source

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel.

open access: yesBlood, 2017
The first edition of the European LeukemiaNet (ELN) recommendations for diagnosis and management of acute myeloid leukemia (AML) in adults, published in 2010, has found broad acceptance by physicians and investigators caring for patients with AML. Recent
H. Döhner   +21 more
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Publicadas nuevas recomendaciones de RCP y Soporte Vital: Conferencia ILCOR 2015

open access: yesRevista Electrónica de AnestesiaR, 1970
El pasado dí­a 15 de octubre de 2015 se han publicado, de forma simultánea en todo el mundo, las nuevas Recomendaciones de Resucitación Cardio-pulmonar (RCP) de 2015 auspiciadas por el International Liaison Committee on Resuscitation (ILCOR).
Fco. Javier García Vega   +1 more
doaj   +1 more source

Caracterización del perfil y remuneración de los pares evaluadores en el área de negocios y management reconocidos por Minciencias, Colombia

open access: yesAiBi Revista de Investigación, Administración e Ingeniería, 2021
El artículo tiene como propósito caracterizar el perfil de pares evaluadores en el área de negocios y management reconocidos por el Ministerio de Ciencia, Tecnología e Innovación (Minciencias), Colombia, y su opinión acerca de la remuneración para la ...
Fabio Orlando Cruz-Páez   +2 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Revisors 2015 [PDF]

open access: yesRubrica Contemporanea, 2016
...
openaire   +3 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Revised Estimates for the Number of Human and Bacteria Cells in the Body

open access: yesbioRxiv, 2016
We critically revisit the “common knowledge” that bacteria outnumber human cells by a ratio of at least 10:1 in the human body. We found the total number of bacteria in the “reference man” to be 3.9·1013, with an uncertainty (SEM) of 25%, and a variation
R. Sender, Shai Fuchs, R. Milo
semanticscholar   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

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