Results 41 to 50 of about 723,158 (319)

Kauravalikoima lisääntyy [PDF]

, 2004
Kauppaan lasketaan tänä vuonna kaksi uutta kauralajiketta: Keskon Svala ja Plantanovan Revisor. Svala menestyy vielä neljännelläkin viljelyvyöhykkeellä.
Kangas, Arjo, Vuorinen, Martti
core  

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Aplicación y ámbito comercial de la Revisoría Fiscal en el contexto nacional [PDF]

, 2013
Este ensayo está sustentado en: La no aplicabilidad del marco legal por parte de comerciantes y Revisores Fiscales, acarreándoles sanciones por parte de los entes de vigilancia y control, así mismo se plantea el respeto por las leyes que regulan el ...
Hernández Gómez, Helmut, Rocha Paez, Walter Fernando   +1 more
core  

Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup

Alzheimer's & Dementia
The National Institute on Aging and the Alzheimer's Association convened three separate work groups in 2011 and single work groups in 2012 and 2018 to create recommendations for the diagnosis and characterization of Alzheimer's disease (AD).
Clifford R Jack, J. S. Andrews, Thomas G. Beach, Teresa Buracchio, B. Dunn, Ana Graf, Oskar Hansson, Carole Ho, William Jagust, E. McDade, J. Molinuevo, O. Okonkwo, Luca Pani, M. Rafii, P. Scheltens, Eric R. Siemers, H. Snyder, R. Sperling, C. Teunissen, Maria C. Carrillo   +19 more
semanticscholar   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Intellectual Coherence in an Evidence Code [PDF]

, 1995
The Federal Rules of Evidence (Federal Rules or Rules) were created in large part to promote uniformity and predictability in federal trials by providing a relatively instructive guide for judges and lawyers concerning the admissibility of evidence.
Rothstein, Paul F
core   +2 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

HUBUNGAN PRILAKU KEPEMIMPINAN KEPALA SEKOLAH DENGAN KINERJA GURU DI SMP NEGERI 2 KECAMATAN KETANGGUNGAN KABUPATEN BREBES [PDF]

, 2012
Oppgavens tema er revisors profesjonelle skepsis. Konseptet profesjonell skepsis spiller en nøkkelrolle for kvaliteten av revisjonen (Boyle & Carpenter, 2015).
Rudi, Silje H. G., Sandvik, Charlotte
core   +1 more source

SQUIRE 2.0 (Standards for QUality Improvement Reporting Excellence): revised publication guidelines from a detailed consensus process

BMJ Quality & Safety, 2015
Since the publication of Standards for QUality Improvement Reporting Excellence (SQUIRE 1.0) guidelines in 2008, the science of the field has advanced considerably. In this manuscript, we describe the development of SQUIRE 2.0 and its key components.
Greg Ogrinc, L. Davies, Daisy Goodman, P. Batalden, F. Davidoff, David P. Stevens   +5 more
semanticscholar   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source