Results 71 to 80 of about 723,158 (319)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
En efterfrågestyrd revision -Behovet av anpassade standarder för revision av mindre företag utifrån revisorns perspektiv [PDF]
, 2017 Bakgrund och problem: Revisorer har uttryckt att det nuvarande revisionsregelverket (ISA) har blivit alltför omfattande, komplext och otympligt vid revision av mindre företag.
Gillmert, Axel, Persson, Henrik
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Resultatføring av inntekter og kostnader før og etter fravalg av revisor i små AS: tyder utviklingen på økte skatteunndragelser? [PDF]
Dette er siste forfatterversjon, etter fagfellevurdering, før publiseringHvis selskaper som velger bort revisor begynner å selge svart eller kreve fradrag for fiktive eller private utgifter etter fravalget av revisor, vil de ha en lavere vekst i ...
Langli, John Christian
core
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
El lavado de activos y la financiación del terrorismo: delito de poco conocimiento por parte de los profesionales de la revisoría fiscal [PDF]
, 2014 Con éste documento se pretende dar a conocer y analizar la actualidad legislativa en Colombia, donde el Revisor Fiscal no tiene intervención por normatividad y por ende su interés en el tema es poco complejo, dejando la responsabilidad de vigilancia ...
Briceño Espinosa, Ana Milena
core
FEBS Open Bio, EarlyView.IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
El enfoque constructivista en el aprendizaje de las competencias de revisión de traducciones [PDF]
, 2011 La consolidación de la figura del revisor en el ámbito de la traducción a raíz de la publicación de la norma europea de traducción EN-15038 ha permitido su aplicación a los nuevos planes de estudio.
Rodríguez Rodríguez, Beatriz María
core +3 more sources